Molecular circuits shared by placental and cancer cells, and their implications in the proliferative, invasive and migratory capacities of trophoblasts

C Ferretti, L Bruni, V Dangles-Marie… - Human reproduction …, 2007 - academic.oup.com
Trophoblast research over the past decades has underlined the striking similarities between
the proliferative, migratory and invasive properties of placental cells and those of cancer …

Natural dietary anti‐cancer chemopreventive compounds: redox‐mediated differential signaling mechanisms in cytoprotection of normal cells versus cytotoxicity in …

S Nair, W Li, ANT KONG - Acta Pharmacologica Sinica, 2007 - Wiley Online Library
Many dietary phytochemicals exhibit health‐beneficial effects including prevention of
diseases such as cancer, as well as neurological, cardiovascular, inflammatory, and …

Metastasis associated lung adenocarcinoma transcript 1 is up-regulated in placenta previa increta/percreta and strongly associated with trophoblast-like cell invasion …

JJ Tseng, YT Hsieh, SL Hsu… - Molecular human …, 2009 - academic.oup.com
Placenta previa increta/percreta (I/P) is a severe form of invasive placentation associated
with massive peripartum hemorrhage, which often requires Cesarean hysterectomy. The …

Epigenetics and the plasticity of differentiation in normal and cancer stem cells

J Lotem, L Sachs - Oncogene, 2006 - nature.com
Embryonic stem cells are characterized by their differentiation to all cell types during
embryogenesis. In adult life, different tissues also have somatic stem cells, called adult stem …

Genes overexpressed in different human solid cancers exhibit different tissue-specific expression profiles

JB Axelsen, J Lotem, L Sachs… - Proceedings of the …, 2007 - National Acad Sciences
We have analyzed gene expression in different normal human tissues and different types of
solid cancers derived from these tissues. The cancers analyzed include brain (astrocytoma …

Systems biology of cancer: entropy, disorder, and selection-driven evolution to independence, invasion and “swarm intelligence”

M Tarabichi, A Antoniou, M Saiselet, JM Pita… - Cancer and Metastasis …, 2013 - Springer
Our knowledge of the biology of solid cancer has greatly progressed during the last few
years, and many excellent reviews dealing with the various aspects of this biology have …

Gene expression signatures in childhood acute leukemias are largely unique and distinct from those of normal tissues and other malignancies

A Andersson, P Edén, T Olofsson, T Fioretos - BMC medical genomics, 2010 - Springer
Background Childhood leukemia is characterized by the presence of balanced
chromosomal translocations or by other structural or numerical chromosomal changes. It is …

The network organization of cancer-associated protein complexes in human tissues

J Zhao, SH Lee, M Huss, P Holme - Scientific reports, 2013 - nature.com
Differential gene expression profiles for detecting disease genes have been studied
intensively in systems biology. However, it is known that various biological functions …

Receptor-Independent Ectopic Activity of Prolactin Predicts Aggressive Lung Tumors and Indicates HDACi-Based Therapeutic Strategies

A Le Bescont, AL Vitte, A Debernardi… - Antioxidants & Redox …, 2015 - liebertpub.com
Aims: Ectopic activation of tissue-specific genes accompanies malignant transformation in
many cancers. Prolactin (PRL) aberrant activation in lung cancer was investigated here to …

[图书][B] Data science for mathematicians

N Carter - 2020 - books.google.com
Mathematicians have skills that, if deepened in the right ways, would enable them to use
data to answer questions important to them and others, and report those answers in …