Phenotypes and biomarkers of diabetic retinopathy

J Cunha-Vaz, L Ribeiro, C Lobo - Progress in retinal and eye research, 2014 - Elsevier
Diabetic retinopathy (DR) remains a major cause of blindness as the prevalence of diabetes
is expected to approximately double globally between 2000 and 2030. DR progresses over …

Imbalance of the nerve growth factor and its precursor as a potential biomarker for diabetic retinopathy

BA Mysona, S Matragoon, M Stephens… - BioMed research …, 2015 - Wiley Online Library
Our previous studies have demonstrated that diabetes‐induced oxidative stress alters
homeostasis of retinal nerve growth factor (NGF) resulting in accumulation of its precursor …

Optical coherence tomography: a concept review

P Serranho, AM Morgado, R Bernardes - Optical coherence tomography: a …, 2012 - Springer
Optical coherence tomography (OCT) is an imaging modality broadly used in biological
tissue imaging. In this chapter, we review the history of OCT and its development throughout …

[图书][B] Ocular drug delivery systems: barriers and application of nanoparticulate systems

D Thassu, GJ Chader - 2012 - books.google.com
Drug discovery for ocular diseases has taken great strides in the last two decades. From
cornea to choroid, new drugs have been formulated to address a great variety of ocular …

Simulation of cellular changes on optical coherence tomography of human retina

M Santos, A Araújo, S Barbeiro… - 2015 37th Annual …, 2015 - ieeexplore.ieee.org
We present a methodology to assess cell level alterations on the human retina responsible
for functional changes observable in the Optical Coherence Tomography data in healthy …

[HTML][HTML] Retinal OCT-Derived Texture Features as Potential Biomarkers for Early Diagnosis and Progression of Diabetic Retinopathy

S Oliveira, P Guimarães, EJ Campos… - … & Visual Science, 2025 - tvst.arvojournals.org
Purpose: Diabetic retinopathy (DR) is usually diagnosed many years after diabetes onset.
Indeed, an early diagnosis of DR remains a notable challenge, and, thus, developing novel …

Diabetic macular edema

C Lobo, I Pires, J Cunha-Vaz - Optical Coherence Tomography: A Clinical …, 2012 - Springer
The optical coherence tomography (OCT), a noninvasive and noncontact diagnostic method,
was introduced in 1995 for imaging macular diseases. In diabetic macular edema (DME) …

Optical coherence tomography: Automatic retina classification through support vector machines

R Bernardes, P Serranho, T Santos, V Gonçalves… - 2012 - repositorioaberto.uab.pt
Optical coherence tomography (OCT) is becoming one of the most important imaging
modalities in ophthalmology due to its non-invasiveness and by allowing the visualisation …

Computer-aided detection of diabetic retinopathy progression

J Cunha-Vaz, R Bernardes, T Santos, C Oliveira… - Digital Teleretinal …, 2012 - Springer
It is considered crucial for diabetic retinopathy (DR) management to identify disease
progression in clinical practice. Automated computer-aided analysis of fundus digital …

From optical coherence tomography to Maxwell's equations

ASFC Silva, AL Correia - 2013 IEEE 3rd Portuguese Meeting in …, 2013 - ieeexplore.ieee.org
Optical Coherence Tomography, OCT, is a relatively recent imaging technique that allows
high resolution imaging of the retina. It relies in certain optical characteristics of light to …