Design concepts of half-sandwich organoruthenium anticancer agents based on bidentate bioactive ligands
The small molecule anticancer agent cisplatin and its Pt (II) analogs carboplatin and
oxaliplatin are widely used to treat a variety of tumorigenic diseases. Despite their structural …
oxaliplatin are widely used to treat a variety of tumorigenic diseases. Despite their structural …
An overview of advancement of organoruthenium (II) complexes as prospective anticancer agents
M Bashir, IA Mantoo, F Arjmand, S Tabassum… - Coordination Chemistry …, 2023 - Elsevier
The successful clinical translation of platinum drugs for cancer treatment has witnessed an
upsurge in the development of metal compounds as therapeutics and diagnostics drugs …
upsurge in the development of metal compounds as therapeutics and diagnostics drugs …
Synthesis of palladium (II) complexes via Michael addition: antiproliferative effects through ROS-mediated mitochondrial apoptosis and docking with SARS-CoV-2
Metal complexes have numerous applications in the current era, particularly in the field of
pharmaceutical chemistry and catalysis. A novel synthetic approach for the same is always a …
pharmaceutical chemistry and catalysis. A novel synthetic approach for the same is always a …
New organoruthenium (II) complexes containing N, X-donor (X= O, S) heterocyclic chelators: synthesis, spectral characterization, in vitro cytotoxicity and apoptosis …
G Kalaiarasi, MM Subarkhan, CKF Safwana… - Inorganica chimica …, 2022 - Elsevier
Four Schiff base ligands namely ((1E)-1-(1-(6-chloro-2-oxo-2H-chromen-3-yl) ethylidene)
semicarbazide)(HL 1),((1E)-1-(1-(6-chloro-2-oxo-2H-chromen-3-yl) ethylidene …
semicarbazide)(HL 1),((1E)-1-(1-(6-chloro-2-oxo-2H-chromen-3-yl) ethylidene …
[HTML][HTML] Advances in thiosemicarbazone metal complexes as anti-lung cancer agents
XG Bai, Y Zheng, J Qi - Frontiers in Pharmacology, 2022 - frontiersin.org
The great success of cisplatin as a chemotherapeutic agent considerably increased
research efforts in inorganic biochemistry to identify more metallic drugs having the potential …
research efforts in inorganic biochemistry to identify more metallic drugs having the potential …
Design and synthesis of heterocyclic azole based bioactive compounds: Molecular structures, quantum simulation, and mechanistic studies through docking as multi …
J Haribabu, V Garisetti, RE Malekshah… - Journal of molecular …, 2022 - Elsevier
Abstract Two heterocyclic azole compounds, 3-(2, 3-dihydrobenzo [d] thiazol-2-yl)-4H-
chromen-4-one (SVS1) and 5-(1H-indol-3-yl)-4-methyl-2, 4-dihydro-3H-1, 2, 4-triazole-3 …
chromen-4-one (SVS1) and 5-(1H-indol-3-yl)-4-methyl-2, 4-dihydro-3H-1, 2, 4-triazole-3 …
Adding diversity to a diruthenium biscyclopentadienyl scaffold via alkyne incorporation: Synthesis and biological studies
G Bresciani, S Boni, T Funaioli, S Zacchini… - Inorganic …, 2023 - ACS Publications
We report the synthesis and the assessment of the anticancer potential of two series of
diruthenium biscyclopentadienyl carbonyl complexes. Novel dimetallacyclopentenone …
diruthenium biscyclopentadienyl carbonyl complexes. Novel dimetallacyclopentenone …
[HTML][HTML] Effect of morphology and (Sn, Cr) doping on in vitro antiproliferation properties of hydrothermally synthesized 1D GaOOH nanostructures
GaOOH powders of submicron dimensions were synthesized through a simple, surfactant-
free hydrothermal synthesis at pH values of 7 and 14. Sn and Cr at concentrations of 2 mol …
free hydrothermal synthesis at pH values of 7 and 14. Sn and Cr at concentrations of 2 mol …
Effect of N-benzyl group in indole scaffold of thiosemicarbazones on the biological activity of their Pd (II) complexes: DFT, biomolecular interactions, in silico docking …
A series of N-benzyl substituted indole-based thiosemicarbazone (TSC) ligands (L4-L6) and
palladium (II) TSC complexes,[Pd (L) 2](1–6)(L= monoanionic bidentate un/N-substituted …
palladium (II) TSC complexes,[Pd (L) 2](1–6)(L= monoanionic bidentate un/N-substituted …
Ruthenium (II)‐Dithiocarbazates as Anticancer Agents: Synthesis, Solution Behavior, and Mitochondria‐Targeted Apoptotic Cell Death
The reaction of the Ru (PPh3) 3Cl2 with HL1− 3− OH (− OH stands for the oxime hydroxyl
group; HL1− OH= diacetylmonoxime‐S‐benzyldithiocarbazonate; HL2− OH …
group; HL1− OH= diacetylmonoxime‐S‐benzyldithiocarbazonate; HL2− OH …