[HTML][HTML] Deep learning in cancer diagnosis, prognosis and treatment selection

KA Tran, O Kondrashova, A Bradley, ED Williams… - Genome Medicine, 2021 - Springer
Deep learning is a subdiscipline of artificial intelligence that uses a machine learning
technique called artificial neural networks to extract patterns and make predictions from …

Multimodal deep learning for biomedical data fusion: a review

SR Stahlschmidt, B Ulfenborg… - Briefings in …, 2022 - academic.oup.com
Biomedical data are becoming increasingly multimodal and thereby capture the underlying
complex relationships among biological processes. Deep learning (DL)-based data fusion …

A roadmap for multi-omics data integration using deep learning

M Kang, E Ko, TB Mersha - Briefings in Bioinformatics, 2022 - academic.oup.com
High-throughput next-generation sequencing now makes it possible to generate a vast
amount of multi-omics data for various applications. These data have revolutionized …

Toward explainable artificial intelligence for precision pathology

F Klauschen, J Dippel, P Keyl… - Annual Review of …, 2024 - annualreviews.org
The rapid development of precision medicine in recent years has started to challenge
diagnostic pathology with respect to its ability to analyze histological images and …

[HTML][HTML] Evaluation and comparison of multi-omics data integration methods for cancer subtyping

R Duan, L Gao, Y Gao, Y Hu, H Xu… - PLoS computational …, 2021 - journals.plos.org
Computational integrative analysis has become a significant approach in the data-driven
exploration of biological problems. Many integration methods for cancer subtyping have …

Advances in bulk and single-cell multi-omics approaches for systems biology and precision medicine

Y Li, L Ma, D Wu, G Chen - Briefings in Bioinformatics, 2021 - academic.oup.com
Multi-omics allows the systematic understanding of the information flow across different
omics layers, while single omics can mainly reflect one aspect of the biological system. The …

[HTML][HTML] Artificial intelligence (AI)-based systems biology approaches in multi-omics data analysis of cancer

N Biswas, S Chakrabarti - Frontiers in Oncology, 2020 - frontiersin.org
Cancer is the manifestation of abnormalities of different physiological processes involving
genes, DNAs, RNAs, proteins, and other biomolecules whose profiles are reflected in …

XOmiVAE: an interpretable deep learning model for cancer classification using high-dimensional omics data

E Withnell, X Zhang, K Sun, Y Guo - Briefings in bioinformatics, 2021 - academic.oup.com
The lack of explainability is one of the most prominent disadvantages of deep learning
applications in omics. This 'black box'problem can undermine the credibility and limit the …

Application of non-negative matrix factorization in oncology: one approach for establishing precision medicine

R Hamamoto, K Takasawa, H Machino… - Briefings in …, 2022 - academic.oup.com
The increase in the expectations of artificial intelligence (AI) technology has led to machine
learning technology being actively used in the medical field. Non-negative matrix …

[HTML][HTML] Variational autoencoders learn transferrable representations of metabolomics data

DP Gomari, A Schweickart, L Cerchietti… - Communications …, 2022 - nature.com
Dimensionality reduction approaches are commonly used for the deconvolution of high-
dimensional metabolomics datasets into underlying core metabolic processes. However …