Raman spectroscopy is a very powerful tool for material analysis, allowing for exploring the
properties of a wide range of different materials. Since its discovery, Raman spectroscopy …

Water is a ubiquitous and vital component of living systems. Hydration, which is the
interaction between water and intracellular biomolecules, plays an important role in cellular …

The cell nucleus is a compartment in which essential processes such as gene transcription
and DNA replication occur. Although the large amount of chromatin confined in the finite …

Liquid–liquid phase separation (LLPS) plays an important role in a variety of biological
processes and is also associated with protein aggregation in neurodegenerative diseases …

We propose a label‐free method for measuring intracellular temperature using a Raman
image of a cell in the O− H stretching band. Raman spectra of cultured cells and the medium …

Probing dynamics of intracellular components using physical chemistry techniques is a
remarkable bottom-up approach for understanding the structures and functions of a …

Water is arguably the most common and yet least understood material on Earth. Indeed, the
biophysical behavior of water in crowded intracellular milieu is a long-debated issue …

Raman hyperspectral microscopy is a valuable tool in biological and biomedical imaging.
Because Raman scattering is often weak in comparison to other phenomena, prevalent …

The term “biological water” means different things to different people (1, 2), but to many, it
simply denotes water in the near vicinity of biological macromolecules. With this terminology …

The physical properties of lipids, such as viscosity, are homeostatically maintained in cells
and are intimately involved in physiological roles. Measurement of the physical properties of …