Understanding adipogenesis, the process of adipocyte development, may provide new ways
to treat obesity and related metabolic diseases. Adipogenesis is controlled by coordinated …

The obesity epidemic represents a critical public health issue worldwide, as it is a vital risk
factor for many diseases, including type 2 diabetes (T2D) and cardiovascular disease …

The epigenomic reader Brd4 is an important drug target for cancers. However, its role in cell
differentiation and animal development remains largely unclear. Using two conditional …

Background Single nucleotide polymorphism (SNP) arrays for domestic cattle have
catalyzed the identification of genetic markers associated with complex traits for inclusion in …

Kaempferol is a natural flavonoid widely found in fruits, vegetables, and tea. Kaempferol
possesses beneficial biological properties such as anti-inflammatory and antioxidant …

Whereas the actions of enhancers in gene transcriptional regulation are well established,
roles of JmjC-domain-containing proteins in mediating enhancer activation remain poorly …

Obesity is one of the biggest public health concerns identified by an increase in adipose
tissue mass as a result of adipocyte hypertrophy and hyperplasia. Pertaining to the …

Stress granules (SG) are membrane-less organelles that are condensates of stalled
translation initiation complexes and mRNAs. SG formation is a cytoprotective response to …

Jumonji C domain-containing (JMJD) proteins are mostly epigenetic regulators that
demethylate histones. However, a hitherto neglected subfamily of JMJD proteins …

Adipose tissue plays central role in determining the gustatory quality of beef, but traditional
Chinese beef cattle have low levels of fat content. We applied RNA-seq to study the …