I. Introduction II. 9S Receptors A. Estrogen receptors (ERs) B. Progesterone receptors (PRs)
C. Androgen receptors (ARs) D. Glucocorticoid receptors (GRs) E. Mineralocorticoid …

Nearly 100 proteins are known to be regulated by hsp90. Most of these substrates or “client
proteins” are involved in signal transduction, and they are brought into complex with hsp90 …

Heat shock and other proteotoxic stresses cause accumulation of nonnative proteins that
trigger activation of heat shock protein (Hsp) genes. A chaperone/Hsp functioning as …

The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that controls
the expression of a diverse set of genes. The toxicity of the potent AhR ligand 2, 3, 7, 8 …

Molecular chaperones are a functionally defined set of proteins which assist the structure
formation of proteins in vivo. Without certain protective mechanisms, such as binding …

Estrogen receptor alpha (ERα) and estrogen receptor beta (ERβ) belong to a superfamily of
nuclear receptors called steroid hormone receptors, which, upon binding ligand, dimerize …

Transcriptional regulation of the human hsp70 gene in response to heat shock and other
forms of physiological stress occurs through the activation of heat shock transcription factor …

BACKGROUND: Heat shock protein 90 (Hsp90) interacts with and stabilizes several
oncogenic protein kinases (eg, p185erbB2, p60v-src, and Raf-1) and is required for the …

Hsp90 is a highly abundant and ubiquitous molecular chaperone which plays an essential
role in many cellular processes including cell cycle control, cell survival, hormone and other …

Transcriptional activity of heat shock (hsp) genes is controlled by a heat-activated, group-
specific transcription factor (s) recognizing arrays of inverted repeats of the element NGAAN …