Recent progress in functionalized and targeted polymersomes and chimeric polymeric nanotheranostic platforms for cancer therapy

M Beygi, F Oroojalian, SS Hosseini… - Progress in Materials …, 2023 - Elsevier
The majority of advances in cancer therapy have been achieved based on developments in
public awareness, as well as novel diagnostic and therapeutic modalities. Treatment …

Exploring giant unilamellar vesicle production for artificial cells—Current challenges and future directions

L Van de Cauter, L van Buren, GH Koenderink… - Small …, 2023 - Wiley Online Library
Creating an artificial cell from the bottom up is a long‐standing challenge and, while
significant progress has been made, the full realization of this goal remains elusive …

A small-molecule carrier for the intracellular delivery of a membrane-impermeable protein with retained bioactivity

X Ma, Z Zhang, A Barba-Bon, D Han, Z Qi, B Ge… - Proceedings of the …, 2024 - pnas.org
Intracellular protein delivery has the potential to revolutionize cell-biological research and
medicinal therapy, with broad applications in bioimaging, disease treatment, and genome …

Membrane models and experiments suitable for studies of the cholesterol bilayer domains

I Mardešić, Z Boban, WK Subczynski, M Raguz - Membranes, 2023 - mdpi.com
Cholesterol (Chol) is an essential component of animal cell membranes and is most
abundant in plasma membranes (PMs) where its concentration typically ranges from 10 to …

Secondary Ion Mass Spectrometry of Single Giant Unilamellar Vesicles Reveals Compositional Variability

DS Grusky, A Bhattacharya… - Journal of the American …, 2023 - ACS Publications
Giant unilamellar vesicles (GUVs) are a widely used model system to interrogate lipid phase
behavior, study biomembrane mechanics, reconstitute membrane proteins, and provide a …

Synthetic Cells Revisited: Artificial Cells Construction Using Polymeric Building Blocks

V Maffeis, L Heuberger, A Nikoletić… - Advanced …, 2024 - Wiley Online Library
The exponential growth of research on artificial cells and organelles underscores their
potential as tools to advance the understanding of fundamental biological processes. The …

Electroformation of Giant Unilamellar Vesicles from Damp Lipid Films Formed by Vesicle Fusion

Z Boban, I Mardešić, SP Jozić, J Šumanovac… - Membranes, 2023 - mdpi.com
Giant unilamellar vesicles (GUVs) are artificial membrane models which are of special
interest to researchers because of their similarity in size to eukaryotic cells. The most …

Optimization of Giant Unilamellar Vesicle Electroformation for Phosphatidylcholine/Sphingomyelin/Cholesterol Ternary Mixtures

Z Boban, I Mardešić, WK Subczynski, D Jozić, M Raguz - Membranes, 2022 - mdpi.com
Artificial vesicles are important tools in membrane research because they enable studying
membrane properties in controlled conditions. Giant unilamellar vesicles (GUVs) are …

[HTML][HTML] Dynamics of giant vesicle assembly from thin lipid films

J Pazzi, AB Subramaniam - Journal of Colloid and Interface Science, 2024 - Elsevier
Abstract Motivation Giant unilamellar vesicles (GUVs), cell-like synthetic micrometer size
structures, assemble when thin lipid films are hydrated in aqueous solutions. Quantitative …

An Efficient Method for the Production of High-Purity Bioinspired Large Unilamellar Vesicles

M Macher, A Obermeier, S Fabritz, M Kube… - ACS Synthetic …, 2024 - ACS Publications
In order to recapitulate complex eukaryotic compartmentalization, synthetic biology aims to
recreate cellular membrane-lined compartments from the bottom-up. Many important cellular …