X-ray diffraction was one of the early methods to be used in solving protein conformation.
The technique can give the atomic coordinates of the protein components and therefore …

Since the middle of 20th century infrared (IR) spectroscopy coupled to microscopy (IR
microspectroscopy) has been recognized as a non destructive, label free, highly sensitive …

In the choice of an estimator for the spectrum of a stationary time series from a finite sample
of the process, the problems of bias control and consistency, or" smoothing," are dominant …

A novel concept in vibrational spectroscopy called two-dimensional infrared (2D IR)
spectroscopy is described. In 2D IR, a spectrum defined by two independent wavenumbers …

Recent years have seen substantial progress toward the application of infrared (IR) and
Raman spectroscopy as useful analytical tools in biomedical research. Vibrational …

The last two decades have seen a great surge of activity in the field of biomembranes [1-3].
Biophysical studies of model and natural membranes have been quite successful in …

The basic knowledge accumulated over the last twenty years on the different vibrations of
polypeptides were reviewed in Chapter 8. Because of the complexity of naturally occurring …

Attenuated total reflection Fourier‐transform infrared spectroscopy of thin hydrated films of
soluble and membrane protein included in a phospholipid bilayer is shown to provide useful …

The use of shifted-spectra, first-derivative spectroscopy (or edge detection), and fast Fourier
transform filtering techniques for fluorescence rejection in Raman spectra is demonstrated …

Spatial resolution is one of the most critical measurement parameters in infrared
microspectroscopy. Due to the distinct levels of morphologic heterogeneity in cells and …