Many observation studies have demonstrated a close relationship between rheumatoid
arthritis (RA) and osteoporosis (OP). However, the causal genetic correlation between RA …

Background: Numerous studies have demonstrated an association between osteoprotegerin
(OPG) polymorphisms (A163G (rs3102735), T245G (rs3134069), T950C (rs2073617) …

Background: The RANKL/RANK/OPG signaling pathway plays a critical role in
osteoclastogenesis and bone remodeling. The associations between sequence variants of …

Background: Postmenopausal osteoporosis is a multifactorial disease. Genetic factors play
an essential role in contributing to bone mineral density (BMD) variability, which ranges from …

Background Otosclerosis (OTSC) is among the most common causes of a late-onset hearing
loss in adults and is characterized by an abnormal bone growth in the otic capsule …

Orthodontic-induced external apical root resorption (EARR) is a severe condition affecting
the roots of the teeth, whose genetic causes have been inconclusive to date. The aim of the …

Osteoporosis is a multifactorial and polygenic disease caused by an imbalance between
osteoclastogenesis and osteoblastogenesis, leading to a decrease in bone mineral density …

Objectives This study was aimed to investigate the association of the single nucleotide
polymorphism of tumor necrosis factor receptor associated factor 6 (TRAF6), rs540386, with …

Wear debris-induced inflammatory osteolysis remains a significant limiting factor for implant
replacement surgeries. Hence, a comprehensive understanding of the complex network of …

Background and purposes Osteoporosis and osteopenia are multifactorial diseases
characterized by low bone mineral density (BMD) and are susceptible to genetic and …