The platelet‑derived growth factor (PDFG) signaling pathway exerts persistent activation in
response to a variety of stimuli and facilitates the progression of hepatic fibrosis. Since this …

Medicinal plants are considered the reservoir of diverse therapeutic agents and have been
traditionally employed worldwide to heal various ailments for several decades. Silymarin is a …

Silymarin flavonolignans are well-known agents that typically possess antioxidative, anti-
inflammatory, and hepatoprotective functions. Recent studies have also documented the …

В настоящем издании проанализированы и систематизированы сведения по
клиническому применению лекарственных средств, для которых гепатотропное …

Inflammatory bowel disease (IBD) is a chronic recurrent inflammation of the gastrointestinal
tract (GIT). IBD patients are susceptible to various infections such as viral infections due to …

COVID-19, the illness caused by infection with the novel coronavirus SARS-CoV-2, is a
rapidly spreading global pandemic in urgent need of effective treatments. Here we present a …

The global burden of chronic liver disease (CLD) is substantial. Due to the limited indication
of and accessibility to antiviral therapy in viral hepatitis and lack of effective pharmacological …

Hepatocellular carcinoma (HCC) is the most common type of liver cancer. The main risk
factors for HCC are alcoholism, hepatitis B virus, hepatitis C virus, nonalcoholic …

Liver disease represents a significant global public health concern. Silybin, derived from
Silybum marianum, has been demonstrated to exhibit a range of beneficial properties …

Liver fibrosis is a wound-healing response to a wide spectrum of chronic liver injuries. It is
characterized by loss of hepatocytes and alteration in hepatic architecture following an …