Intercellular pathways of cancer treatment-related cardiotoxicity and their therapeutic implications: the paradigm of radiotherapy

S Logotheti, A Pavlopoulou, HK Rudsari… - Pharmacology & …, 2024 - Elsevier
Advances in cancer therapeutics have improved patient survival rates. However, cancer
survivors may suffer from adverse events either at the time of therapy or later in life …

The role of TGF-β3 in radiation response

I Hanson, KE Pitman, NFJ Edin - International journal of molecular …, 2023 - mdpi.com
Transforming growth factor-beta 3 (TGF-β3) is a ubiquitously expressed multifunctional
cytokine involved in a range of physiological and pathological conditions, including …

Effects of acute low-moderate dose ionizing radiation to human brain organoids

FA Oyefeso, G Goldberg, NYPS Opoku, M Vazquez… - Plos one, 2023 - journals.plos.org
Human exposure to low-to-moderate dose ionizing radiation (LMD-IR) is increasing via
environmental, medical, occupational sources. Acute exposure to LMD-IR can cause …

Ionizing Radiation, Antioxidant Response and Oxidative Damage: Radiomodulators

E Obrador, A Montoro - Antioxidants, 2023 - mdpi.com
Ionizing radiation (IR) is the energy released by atoms in the form of electromagnetic waves
(eg, X or gamma rays) or particle radiation (alpha, beta, electrons, protons, neutrons …

Molecular Biomarkers for Predicting Cancer Patient Radiosensitivity and Radiotoxicity in Clinical Practice

A Gkikoudi, SA Kalospyros, S Triantopoulou… - Applied Sciences, 2023 - mdpi.com
Radiotherapy (RT) is a major part of cancer treatment. The reported variability in patient
response to this modality can interfere with the continuation of best-possible care, promote …

Molecular Mechanisms of Resistance to Ionizing Radiation in S. cerevisiae and Its Relationship with Aging, Oxidative Stress, and Antioxidant Activity

A González-Vidal, S Mercado-Sáenz… - Antioxidants, 2023 - mdpi.com
The repair of the damage produced to the genome and proteome by the action of ionizing
radiation, oxidizing agents, and during aging is important to maintain cellular homeostasis …

Effects of cyclophosphamide and mitomycin C on radiation-induced transcriptional biomarkers in human lymphoblastoid cells

S Li, TJ Cai, X Lu, M Tian, QJ Liu - International Journal of …, 2023 - Taylor & Francis
Purpose Ionizing radiation (IR)-induced transcriptional changes are considered a potential
biodosimetry for dose evaluation and health risk monitoring of acute or chronic radiation …

Role of TLR4 signaling pathway in the mitigation of damaged lung by low‐dose gamma irradiation

HA Fahmy, MA Mohamed… - Cell Biochemistry and …, 2023 - Wiley Online Library
Organisms frequently suffer negative effects from large doses of ionizing radiation. However,
radiation is not as hazardous at lower doses as was once believed. The current study aims …

Construction of dose prediction model and identification of sensitive genes for space radiation based on single-sample networks under spaceflight conditions

Y Zhang, X Du, L Zhao, Y Sun - International Journal of Radiation …, 2024 - Taylor & Francis
Purpose To identify sensitive genes for space radiation, we integrated the transcriptomic
samples of spaceflight mice from GeneLab and predicted the radiation doses absorbed by …

Targeted lipidomics-based study of radiation-induced metabolite profiles changes in plasma of total body irradiation cases

Q Chen, H Zhao, C Xi, TJ Cai, L Gao… - International Journal of …, 2024 - Taylor & Francis
Purpose Lipidomics is an important tool for triaging exposed individuals, and helps early
adoption of prevention and control strategies. The purpose of this study was to screen …