Antimicrobial resistance monitoring of water environments: a framework for standardized methods and quality control

K Liguori, I Keenum, BC Davis, J Calarco… - … science & technology, 2022 - ACS Publications
Antimicrobial resistance (AMR) is a grand societal challenge with important dimensions in
the water environment that contribute to its evolution and spread. Environmental monitoring …

Fate and toxicity of pharmaceuticals in water environment: an insight on their occurrence in South Asia

HK Khan, MYA Rehman, RN Malik - Journal of environmental management, 2020 - Elsevier
Pharmaceutically active compounds are newly recognized micropollutants which are
ubiquitous in aquatic environment mainly due to direct discharge of treated and untreated …

An omics-based framework for assessing the health risk of antimicrobial resistance genes

AN Zhang, JM Gaston, CL Dai, S Zhao, M Poyet… - Nature …, 2021 - nature.com
Antibiotic resistance genes (ARGs) are widespread among bacteria. However, not all ARGs
pose serious threats to public health, highlighting the importance of identifying those that are …

DeepARG: a deep learning approach for predicting antibiotic resistance genes from metagenomic data

G Arango-Argoty, E Garner, A Pruden, LS Heath… - Microbiome, 2018 - Springer
Background Growing concerns about increasing rates of antibiotic resistance call for
expanded and comprehensive global monitoring. Advancing methods for monitoring of …

ARGs-OAP v2. 0 with an expanded SARG database and Hidden Markov Models for enhancement characterization and quantification of antibiotic resistance genes in …

X Yin, XT Jiang, B Chai, L Li, Y Yang, JR Cole… - …, 2018 - academic.oup.com
Motivation Much global attention has been paid to antibiotic resistance in monitoring its
emergence, accumulation and dissemination. For rapid characterization and quantification …

Wastewater treatment plant resistomes are shaped by bacterial composition, genetic exchange, and upregulated expression in the effluent microbiomes

F Ju, K Beck, X Yin, A Maccagnan… - The ISME …, 2019 - academic.oup.com
Wastewater treatment plants (WWTPs) are implicated as hotspots for the dissemination of
antibacterial resistance into the environment. However, the in situ processes governing …

Co-occurrence of antibiotic and metal resistance genes revealed in complete genome collection

LG Li, Y Xia, T Zhang - The ISME journal, 2017 - academic.oup.com
The high frequency of antibiotic resistance is a global public health concern. More seriously,
widespread metal pressure in the environment may facilitate the proliferation of antibiotic …

A reservoir of 'historical'antibiotic resistance genes in remote pristine Antarctic soils

MW Van Goethem, R Pierneef, OKI Bezuidt… - Microbiome, 2018 - Springer
Background Soil bacteria naturally produce antibiotics as a competitive mechanism, with a
concomitant evolution, and exchange by horizontal gene transfer, of a range of antibiotic …

Deciphering of microbial community and antibiotic resistance genes in activated sludge reactors under high selective pressure of different antibiotics

R Zhao, J Feng, J Liu, W Fu, X Li, B Li - Water Research, 2019 - Elsevier
Currently, the effects of high antibiotic concentrations on the performance of microbiota and
antibiotic resistance genes (ARGs) in activated sludge (AS) process are not well …

Toward a comprehensive strategy to mitigate dissemination of environmental sources of antibiotic resistance

PJ Vikesland, A Pruden, PJJ Alvarez, D Aga… - 2017 - ACS Publications
Antibiotic resistance is a pervasive global health threat. To combat the spread of resistance,
it is necessary to consider all possible sources and understand the pathways and …