Chronic prurigo is a distinct disease defined by the presence of chronic pruritus for at least 6
weeks, a history and/or signs of repeated scratching, and multiple localized or generalized …

Pruritus (or itch) is an unpleasant sensation leading to a desire to scratch. In the epidermis,
there are selective C or Aδ epidermal nerve endings that are pruriceptors. At their other …

Atopic dermatitis (AD) is a chronic eczematous disease with various types of rash, erythema,
edema/papulation, excoriation, or lichenification. Janus kinase 1 inhibitor upadacitinib is …

Purpose To investigate the therapeutic effectiveness and safety of Janus kinase 1 inhibitor
upadacitinib in adolescent patients with atopic dermatitis (AD). Patients and Methods This …

Merkel cells (MCs) are rare multimodal epidermal sensory cells. Due to their interactions
with slowly adapting type 1 (SA1) Aβ low-threshold mechanoreceptor (Aβ-LTMRs) afferents …

Background Patients receiving epidural or intrathecal opioids administration for neuraxial
analgesia frequently suffer from an irritating itch. STING (stimulator of interferon genes), an …

Itch is a common sensation which is amenable to disabling patients' life under pathological
and chronic conditions. Shared assertion easily limits itch to chemical itch, without …

Introduction: Repeated skin contact to detergents causes chronic irritant contact dermatitis
(ICD) associated with itch sensation and eczema. However, the mechanisms of detergent …

Purpose The without a time limitation. Most recent search was performed on 1st June 2022.
Results Thorough history and physical examination are very important in view of multiple …

Itch (pruritus) is a sensation that drives a desire to scratch, a behavior observed in many
animals. Although generally short-lasting and not causing harm, there are several …