In this study on healthy male mice using confocal imaging of dye spreading in the brain and
its further accumulation in the peripheral lymphatics, we demonstrate stronger effects of …

Electrophysiological methods of research are widely used in neurobiology. To assess the
bioelectrical activity of the brain in small laboratory animals, electrocorticography (ECoG) is …

Mutations in the SYNGAP1 gene are one of the common predictors of neurodevelopmental
disorders, commonly resulting in individuals developing autism, intellectual disability …

The proportion, number of bouts, and mean bout duration of different vigilance states (Wake,
NREM, REM) are useful indices of dynamics in experimental sleep research. These metrics …

Most current methods determine sleep and awake stages in rodents by using subjective
thresholding methods. In contrast, we implemented objective thresholding algorithms based …

Rodent electroencephalography (EEG) in preclinical research is frequently conducted in
behaving animals. However, the difficulty inherent in identifying EEG epochs associated with …

Independent automated scoring of sleep-wake and seizures have recently been achieved;
however, the combined scoring of both states has yet to be reported. Mouse models of …

随着人们睡眠问题的日益突出, 随着化学合成的镇静催眠药物缺点的日益显现,
具有改善睡眠功能的中草药受到越来越多人的关注, 大量具有改善睡眠功能的中草药被发现并 …

Rodent electroencephalography (EEG) in preclinical research is frequently conducted in
behaving animals. However, the difficulty inherent in identifying EEG epochs associated with …

Alzheimer's disease (AD) is an aging-related neurodegenerative disorder the main
hallmarks of which are increased cerebral level of β-amyloid (Aβ) peptides, amyloid …