Vasoplegic syndrome (VS) is a common complication following cardiovascular surgery with
cardiopulmonary bypass (CPB), and its incidence varies from 5 to 44%. It is defined as a …

OBJECTIVES: The effectiveness of CytoSorb at removing inflammatory mediators in critically
ill patients is controversial. DATA SOURCES: Electronic databases were searched from …

The newly emerged coronavirus (SARS-CoV-2) is virulent, contagious, and has rapidly
gained many mutations, which makes it highly infectious and swiftly transmissible around …

Cell directed therapy is an evolving therapeutic approach to treat organ dysfunction arising
from hyperinflammation and cytokine storm by processing immune cells in an extracorporeal …

Background ECMO support is associated with the development of a systemic hyper‐
inflammatory response, which may become quite significant and extreme in some cases. We …

Background Extracorporeal blood purification has been widely used in intensive care
medicine, nephrology, toxicology, and other fields. During the last decade, with the …

Objective: To analyze the effect of CytoSorb® on mortality, interleukin levels, vasopressor
use and adverse events in patients with sepsis. Methods: We searched MEDLINE®, Embase …

Sepsis poses a significant threat to human health due to its high morbidity and mortality
rates worldwide. Traditional diagnostic methods for identifying sepsis or its causative …

Extracorporeal organ support (ECOS) has made remarkable progress over the last few
years. Renal replacement therapy, introduced a few decades ago, was the first available …

Management of acute respiratory distress syndrome (ARDS) represents one of the greatest
challenges in intensive care and despite all efforts mortality remains high. One common …