Multi-epitope vaccine design against monkeypox virus via reverse vaccinology method exploiting immunoinformatic and bioinformatic approaches

K Bhattacharya, IM Shamkh, MS Khan, MM Lotfy… - Vaccines, 2022 - mdpi.com
(1) Background: The monkeypox virus is a zoonotic orthopox DNA virus that is closely linked
to the virus. In light of the growing concern about this virus, the current research set out to …

Vaccinomics to design a multi-epitope-based vaccine against monkeypox virus using surface-associated proteins

S Khan, M Irfan, AR Hameed, A Ullah… - Journal of …, 2023 - Taylor & Francis
In 2022, the ongoing multi-country outbreak of monkeypox virus—now occurring outside
Africa, too is a global health concern. Monkeypox is a zoonotic virus, which causes disease …

Designing a novel chimeric multi-epitope vaccine subunit against Staphylococcus argenteus through artificial intelligence approach integrating pan-genome analysis …

M Naveed, S Mahmood, T Aziz, A Azeem… - Journal of …, 2024 - Taylor & Francis
Staphylococcus argenteus is a newly identified pathogen that causes respiratory tract
infections, skin infections, such as cellulitis, abscesses, and impetigo, and currently, there is …

Onco-Pathogen mediated cancer progression and associated signaling pathways in cancer development

S Kannampuzha, AV Gopalakrishnan, H Padinharayil… - Pathogens, 2023 - mdpi.com
Infection with viruses, bacteria, and parasites are thought to be the underlying cause of
about 8–17% of the world's cancer burden, ie, approximately one in every five malignancies …

Elucidation of novel compounds and epitope-based peptide vaccine design against C30 endopeptidase regions of SARS-CoV-2 using immunoinformatics …

S Marriam, MS Afghan, M Nadeem, M Sajid… - Frontiers in Cellular …, 2023 - frontiersin.org
There has been progressive improvement in immunoinformatics approaches for epitope-
based peptide design. Computational-based immune-informatics approaches were applied …

Computational exploration and design of a multi-epitopes vaccine construct against Chlamydia psittaci

AM Alsubaiyel, SI Bukhari - Journal of Biomolecular Structure and …, 2024 - Taylor & Francis
Chlamydia psittaci is an intracellular pathogen and causes variety of deadly infections in
humans. Antibiotics are effective against C. psittaci however high percentage of resistant …

Reverse Vaccinology and Immunoinformatic Assisted Designing of a Multi-Epitopes Based Vaccine Against Nosocomial Burkholderia cepacia

N Alsowayeh, A Albutti, ST Al-Shouli - Frontiers in Microbiology, 2022 - frontiersin.org
Burkholderia cepacia is a Gram-negative nosocomial pathogen and is considered as a
troublesome bacterium due to its resistance to many common antibiotics. There is no …

Computational study to investigate Proteus mirabilis proteomes for multi-epitope vaccine construct design

A Ullah, S Ullah Khan, MU Haq, S Ahmad… - Journal of …, 2023 - Taylor & Francis
Proteus mirabilis is a gram-negative bacterium particularly known for its unique swarming
ability. The swarming gives the bacteria ability to enhance adherence to the catheter surface …

Immunoinformatics-and bioinformatics-assisted computational designing of a novel multiepitopes vaccine against cancer-causing Merkel cell polyomavirus

NM Almansour - Frontiers in Microbiology, 2022 - frontiersin.org
Merkel cell polyomavirus (MCV) contains double-stranded DNA as its genome and is the
fifth polyomavirus that infects humans. The virus causes Merkel cell carcinoma (aggressive …

Design of a Multi-Epitopes Based Chimeric Vaccine against Enterobacter cloacae Using Pan-Genome and Reverse Vaccinology Approaches

WAI Al-Megrin, A Karkashan, AM Alnuqaydan… - Vaccines, 2022 - mdpi.com
Enterobacter cloacae (EC) is a significant emerging pathogen that is occasionally
associated with lung infection, surgical site infection, urinary infection, sepsis, and outbreaks …