Mechanisms of mechanical overload-induced skeletal muscle hypertrophy: current understanding and future directions

MD Roberts, JJ McCarthy… - Physiological …, 2023 - journals.physiology.org
Mechanisms underlying mechanical overload-induced skeletal muscle hypertrophy have
been extensively researched since the landmark report by Morpurgo (1897) of “work …

Extra virgin olive oil (EVOO), a Mediterranean diet component, in the management of muscle mass and function preservation

S Salucci, A Bartoletti-Stella, A Bavelloni, B Aramini… - Nutrients, 2022 - mdpi.com
Aging results in a progressive decline in skeletal muscle mass, strength and function, a
condition known as sarcopenia. This pathological condition is due to multifactorial …

Antibody blockade of activin type II receptors preserves skeletal muscle mass and enhances fat loss during GLP-1 receptor agonism

E Nunn, N Jaiswal, M Gavin, K Uehara… - Molecular …, 2024 - Elsevier
Objective Glucagon-like peptide 1 (GLP-1) receptor agonists reduce food intake, producing
remarkable weight loss in overweight and obese individuals. While much of this weight loss …

Sarcopenia: Molecular regulatory network for loss of muscle mass and function

J Wu, P Ding, H Wu, P Yang, H Guo, Y Tian… - Frontiers in …, 2023 - frontiersin.org
Skeletal muscle is the foundation of human function and plays a key role in producing
exercise, bone protection, and energy metabolism. Sarcopenia is a systemic disease, which …

Effect of dietary arginine supplementation on protein synthesis, meat quality and flavor in growing lambs

L Dou, L Sun, C Liu, L Su, X Chen, Z Yang, G Hu… - Meat Science, 2023 - Elsevier
This study aimed to assess the effect of dietary arginine supplementation on protein
synthesis, meat quality and flavor in lambs. Eighteen Dorper (♂)× Small Tailed Han sheep …

Depressed Protein Synthesis and Anabolic Signaling Potentiate ACL Tear–Resultant Quadriceps Atrophy

AR Keeble, CR Brightwell, CM Latham… - … American journal of …, 2023 - journals.sagepub.com
Background: Anterior cruciate ligament (ACL) tear (ACLT) leads to protracted quadriceps
muscle atrophy. Protein turnover largely dictates muscle size and is highly responsive to …

Post-natal muscle growth and protein turnover: a narrative review of current understanding

DJ Millward - Nutrition research reviews, 2024 - cambridge.org
A model explaining the dietary-protein-driven post-natal skeletal muscle growth and protein
turnover in the rat is updated, and the mechanisms involved are described, in this narrative …

[HTML][HTML] The role of mTORC1 in the regulation of skeletal muscle mass

SC Bodine - Faculty Reviews, 2022 - ncbi.nlm.nih.gov
Skeletal muscle mass is a very plastic characteristic of skeletal muscle and is regulated by
signaling pathways that control the balance between anabolic and catabolic processes. The …

Quercetin alleviated inflammasome-mediated pyroptosis and modulated the mTOR/P70S6/P6/eIF4E/4EBP1 pathway in ischemic stroke

A Alattar, R Alshaman, YS Althobaiti, GM Soliman… - Pharmaceuticals, 2023 - mdpi.com
Stroke ranks as the world's second most prevalent cause of mortality, and it represents a
major public health concern with profound economic and social implications. In the present …

Lespedeza bicolor extract supplementation reduced hyperglycemia-induced skeletal muscle damage by regulation of AMPK/SIRT/PGC1α–related energy metabolism …

H Lee, SY Kim, Y Lim - Nutrition Research, 2023 - Elsevier
Lespedeza bicolor (LB) is known to have antidiabetic activities; however, the underlying
molecular mechanisms of LB in hyperglycemia-induced skeletal muscle damage is unclear …