Liver fibrosis resulting from chronic liver injury are major causes of morbidity and mortality
worldwide. Among causes of hepatic fibrosis, viral infection is most common (hepatitis B and …

Primary biliary cirrhosis (PBC) is a chronic inflammatory autoimmune disease that mainly
targets the cholangiocytes of the interlobular bile ducts in the liver. The condition primarily …

This American Association for the Study of Liver Diseases (AASLD) 2018 Practice Guidance
on Primary Biliary Cholangitis (PBC) is an update of the PBC guidelines published in 2009 …

Liver disease is the twelfth commonest cause of mortality in adults in the United States,
resulting in 34,000 deaths annually from cirrhosis. 7 In addition, the rising incidence of HCC …

Background & Aims We evaluated the efficacy and safety of obeticholic acid (OCA, α-
ethylchenodeoxycholic acid) in a randomized controlled trial of patients with primary biliary …

Practice Guidelines 1;(3) guideline policies, including the AASLD Policy on the
Development and Use of Practice Guidelines and the American Gastroenterological …

BACKGROUND & AIMS: The biochemical response to ursodeoxycholic acid (UDCA) in
primary biliary cirrhosis (PBC) correlates with the long-term prognosis and thus could allow …

Background In the background of availability of better treatments for specific liver diseases
and listing of nonalcoholic steatohepatitis (NASH) as an etiology for liver transplantation …

Primary biliary cirrhosis is a chronic liver disease characterised by intrahepatic bile-duct
destruction, cholestasis, and, in some cases, cirrhosis. Evidence supporting the autoimmune …

Primary biliary cirrhosis (PBC) is a chronic liver disease characterized by the immune
mediated destruction of small intrahepatic bile duct epithelial cells leading to cholestasis …