Prognostic role of neutrophil-to-lymphocyte ratio in solid tumors: a systematic review and meta-analysis

AJ Templeton, MG McNamara, B Šeruga… - Journal of the …, 2014 - academic.oup.com
Background Inflammation may play an important role in cancer progression, and a high
neutrophil-to-lymphocyte ratio (NLR) has been reported to be a poor prognostic indicator in …

[HTML][HTML] Obesity-induced TNFα and IL-6 signaling: the missing link between obesity and inflammation—driven liver and colorectal cancers

L Kern, MJ Mittenbühler, AJ Vesting, AL Ostermann… - Cancers, 2019 - mdpi.com
Cancers | Free Full-Text | Obesity-Induced TNFα and IL-6 Signaling: The Missing Link between
Obesity and Inflammation—Driven Liver and Colorectal Cancers Next Article in Journal Effects …

Association of systemic inflammation and sarcopenia with survival in nonmetastatic colorectal cancer: results from the C SCANS study

EMC Feliciano, CH Kroenke, JA Meyerhardt… - JAMA …, 2017 - jamanetwork.com
Importance Systemic inflammation and sarcopenia are easily evaluated, predict mortality in
many cancers, and are potentially modifiable. The combination of inflammation and …

[HTML][HTML] Systemic inflammation in colorectal cancer: Underlying factors, effects, and prognostic significance

AE Tuomisto, MJ Mäkinen… - World journal of …, 2019 - ncbi.nlm.nih.gov
Systemic inflammation is a marker of poor prognosis preoperatively present in around 20%-
40% of colorectal cancer patients. The hallmarks of systemic inflammation include an …

The systemic inflammation-based neutrophil–lymphocyte ratio: experience in patients with cancer

GJK Guthrie, KA Charles, CSD Roxburgh… - Critical reviews in …, 2013 - Elsevier
There is increasing and consistent evidence that cancer-associated inflammation is a key
determinant of outcome in patients with cancer. Various markers of inflammation have been …

Cytokine-mediated crosstalk between immune cells and epithelial cells in the gut

M Mahapatro, L Erkert, C Becker - Cells, 2021 - mdpi.com
Cytokines are small proteins that are secreted by a vast majority of cell types in the gut. They
not only establish cell-to-cell interactions and facilitate cellular signaling, but also regulate …

Average values and racial differences of neutrophil lymphocyte ratio among a nationally representative sample of United States subjects

B Azab, M Camacho-Rivera, E Taioli - PloS one, 2014 - journals.plos.org
Introduction Several studies reported the negative impact of elevated neutrophil/lymphocyte
ratio (NLR) on outcomes in many surgical and medical conditions. Previous studies used …

Cytokine-induced modulation of colorectal cancer

LF Mager, MH Wasmer, TT Rau, P Krebs - Frontiers in oncology, 2016 - frontiersin.org
The emergence of novel immunomodulatory cancer therapies over the last decade, above
all immune checkpoint blockade, has significantly advanced tumor treatment. For colorectal …

Predictive and sensitive biomarkers for thyroid dysfunctions during treatment with immune‐checkpoint inhibitors

C Kurimoto, H Inaba, H Ariyasu, H Iwakura… - Cancer …, 2020 - Wiley Online Library
Immune‐related adverse events (irAEs) are often seen during immune‐checkpoint inhibitor
(ICI) treatment of various malignancies. Endocrine irAEs including thyroid dysfunctions are …

Neutrophil–lymphocyte ratio (NLR), platelet–lymphocyte ratio (PLR) and lymphocyte–monocyte ratio (LMR) in predicting systemic inflammatory response syndrome …

A Kriplani, S Pandit, A Chawla, JJ de la Rosette… - Urolithiasis, 2022 - Springer
The objective of this prospective observational study was to assess the clinical significance
of neutrophil–lymphocyte ratio (NLR), platelet–lymphocyte ratio (PLR) and lymphocyte …