HOTAIR: an oncogenic long non-coding RNA in human cancer

Q Tang, SS Hann - Cellular Physiology and Biochemistry, 2018 - karger.com
Abstract Long non-coding RNAs (LncRNAs) represent a novel class of noncoding RNAs that
are longer than 200 nucleotides without protein-coding potential and function as novel …

Long noncoding RNA and cancer: a new paradigm

A Bhan, M Soleimani, SS Mandal - Cancer research, 2017 - AACR
In addition to mutations or aberrant expression in the protein-coding genes, mutations and
misregulation of noncoding RNAs, in particular long noncoding RNAs (lncRNA), appear to …

HOTAIR LncRNA: a novel oncogenic propellant in human cancer

T Rajagopal, S Talluri, RL Akshaya, NR Dunna - Clinica chimica acta, 2020 - Elsevier
Long non-coding RNAs (lncRNAs) are an important novel class of non-coding RNAs having
lengths of 200 nucleotides and low expression. The HOX Transcript Antisense Intergenic …

[HTML][HTML] Regulation of lncRNA and its role in cancer metastasis

J Li, H Meng, Y Bai, K Wang - Oncology research, 2016 - ncbi.nlm.nih.gov
Metastasis is the primary cause of cancer-related death all over the world. Metastasis is a
process by which cancer spreads from the place at which it first arose to distant locations in …

The dark matter of the cancer genome: aberrations in regulatory elements, untranslated regions, splice sites, non‐coding RNA and synonymous mutations

S Diederichs, L Bartsch, JC Berkmann… - EMBO molecular …, 2016 - embopress.org
Cancer is a disease of the genome caused by oncogene activation and tumor suppressor
gene inhibition. Deep sequencing studies including large consortia such as TCGA and …

LncRNAs with miRNAs in regulation of gastric, liver, and colorectal cancers: updates in recent years

C Tam, JH Wong, SKW Tsui, T Zuo, TF Chan… - Applied microbiology and …, 2019 - Springer
Long noncoding RNA (lncRNA) is a kind of RNAi molecule composed of hundreds to
thousands of nucleotides. There are several major types of functional lncRNAs which …

Association of well-characterized lung cancer lncRNA polymorphisms with lung cancer susceptibility and platinum-based chemotherapy response

WJ Gong, JY Yin, XP Li, C Fang, D Xiao, W Zhang… - Tumor Biology, 2016 - Springer
Long non-coding RNAs (lncRNAs) play important roles in carcinogenesis and drug efficacy.
Platinum-based chemotherapy is first-line treatment for lung cancer chemotherapy. In this …

LncRNAs and cancer

R Zhang, LQ Xia, WW Lu, J Zhang… - Oncology …, 2016 - spandidos-publications.com
Long non-coding RNAs (lncRNAs) are a group of non-coding RNAs composed of> 200
nucleotides. Recent studies have revealed that lncRNAs exert an important role in the …

Long noncoding RNAs in aging and age-related diseases

S Kour, PC Rath - Ageing research reviews, 2016 - Elsevier
Aging is the universal, intrinsic, genetically-controlled, evolutionarily-conserved and time-
dependent intricate biological process characterised by the cumulative decline in the …

Long non-coding RNAs: a novel paradigm for toxicology

JL Dempsey, JY Cui - Toxicological Sciences, 2017 - academic.oup.com
Long non-coding RNAs (lncRNAs) are over 200 nucleotides in length and are transcribed
from the mammalian genome in a tissue-specific and developmentally regulated pattern …