The current opioid epidemic is one of the most severe public health crisis in US history.
Responding to it has been difficult due to its rapidly changing nature and the severity of its …

Opioid use disorder is characterised by the persistent use of opioids despite the adverse
consequences of its use. The disorder is associated with a range of mental and general …

Importance Medication for opioid use disorder (MOUD) is the criterion standard treatment for
opioid use disorder (OUD), but nationally representative studies of MOUD use in the US are …

Background Retention in opioid substitution (OST) treatment is associated with substantial
reductions in all cause and overdose mortality. This systematic review aims to identify both …

Amid worsening opioid overdose death rates, the nation continues to face a persistent
addiction treatment gap limiting access to quality care for opioid use disorder (OUD). Three …

Importance Opioid overdose deaths in the United States continue to increase, reflecting a
growing need to treat those with opioid use disorder (OUD). Little is known about counties …

Objectives. To estimate health outcomes of policies to mitigate the opioid epidemic.
Methods. We used dynamic compartmental modeling of US adults, in various pain, opioid …

The goal of this guideline1 is to improve the quality of care and treatment outcomes for
patients with alcohol use disorder (AUD), as defined by DSM-5 (American Psychiatric …

At least 2.3 million people in the US have an opioid use disorder, less than 40% of whom
receive evidence-based treatment. Buprenorphine used as part of medication-assisted …

This study examined the state of the literature on the effectiveness of medication assisted
treatment (MAT; methadone, buprenorphine, naltrexone) delivered in prisons and jails on …