Concepts of nanoparticle cellular uptake, intracellular trafficking, and kinetics in nanomedicine

ND Donahue, H Acar, S Wilhelm - Advanced drug delivery reviews, 2019 - Elsevier
Nanoparticle-based therapeutics and diagnostics are commonly referred to as
nanomedicine and may significantly impact the future of healthcare. However, the clinical …

An overview on nanoparticles used in biomedicine and their cytotoxicity

M Nikzamir, A Akbarzadeh, Y Panahi - Journal of Drug Delivery Science …, 2021 - Elsevier
Nanotechnology is the development of engineered nanoparticles to use in biomedical
applications. Nanoparticles have unique physicochemical properties for use in biomedicine …

A review: Using nanoparticles to enhance absorption and bioavailability of phenolic phytochemicals

Z Li, H Jiang, C Xu, L Gu - Food Hydrocolloids, 2015 - Elsevier
Phenolic phytochemicals have been of particular interests in food and pharmaceutical fields
because they have potential to reduce the incidences of coronary heart disease, diabetes …

[HTML][HTML] Different endocytotic uptake mechanisms for nanoparticles in epithelial cells and macrophages

DA Kuhn, D Vanhecke, B Michen… - Beilstein journal of …, 2014 - beilstein-journals.org
Precise knowledge regarding cellular uptake of nanoparticles is of great importance for
future biomedical applications. Four different endocytotic uptake mechanisms, that is …

Understanding cellular interactions with nanomaterials: Towards a rational design of medical nanodevices

F Villanueva-Flores, A Castro-Lugo, OT Ramírez… - …, 2020 - iopscience.iop.org
Biomedical applications increasingly require fully characterized new nanomaterials. There is
strong evidence showing that nanomaterials not only interact with cells passively but also …

Uptake of engineered gold nanoparticles into mammalian cells

LA Dykman, NG Khlebtsov - Chemical reviews, 2014 - ACS Publications
In the past decade, mammalian cells have increasingly encountered gold nanoparticles
(GNPs), owing to the active development of nanomedicine. 1− 3 GNPs have been more and …

Hyaluronic acid engineered nanomicelles loaded with 3, 4-difluorobenzylidene curcumin for targeted killing of CD44+ stem-like pancreatic cancer cells

P Kesharwani, S Banerjee, S Padhye… - …, 2015 - ACS Publications
Cancer stem-like cells (CSLCs) play a pivotal role in acquiring multidrug resistant (MDR)
phenotypes. It has been established that pancreatic cancers overexpressing CD44 …

Parenterally administrable nano-micelles of 3, 4-difluorobenzylidene curcumin for treating pancreatic cancer

P Kesharwani, S Banerjee, S Padhye, FH Sarkar… - Colloids and Surfaces B …, 2015 - Elsevier
Pancreatic cancer remains one of the most devastating diseases in terms of patient mortality
rates for which current treatment options are very limited. 3, 4-Difluorobenzylidene curcumin …

Clathrin‐Mediated Endocytosis of Gold Nanoparticles In Vitro

CT Ng, FMA Tang, JJ Li, C Ong, LLY Yung… - The anatomical …, 2015 - Wiley Online Library
Gold nanoparticles (AuNPs) have potential biomedical and scientific applications. In this
study, we evaluated the uptake and internalization of FBS‐coated 20 nm AuNPs into lung …

Gold nanoparticles–biomembrane interactions: From fundamental to simulation

E Okoampah, Y Mao, S Yang, S Sun, C Zhou - Colloids and Surfaces B …, 2020 - Elsevier
Abstract Gold Nanoparticles (AuNPs) are a class of promising nanomaterial for biomedical
applications ranging from bioimaging, drug delivery to phototherapy because of their …