Retroviruses can cause diseases such as AIDS, leukemia, and tumors, but are also used as
vectors for human gene therapy. All retroviruses, except foamy viruses, package two copies …

We report the first biological evaluation the 1, 2, 3-thiaselenazole class of compound and
utilising a concise synthetic approach of sulfur extrusion, selenium insertion of the 1, 2, 3 …

One of the striking features of human immunodeficiency virus (HIV) is the capsid, a fullerene
cone comprised of pleomorphic capsid protein (CA) that shields the viral genome and …

A diverse library of 5‐thieno‐, 5‐oxo‐, and 5‐imino‐1, 2, 3‐dithiazole derivatives was
synthesized and evaluated for efficacy against the feline immunodeficiency virus (FIV) as a …

We disclose a series of potent anti-viral 1, 2, 3-dithiazoles, accessed through a succinct
synthetic approach from 4, 5-dichloro-1, 2, 3-dithiazolium chloride (Appel's salt). A series of …

A small diverse library of pentathiepin derivatives were prepared to evaluate their efficacy
against the nucleocapsid protein function of the feline immunodeficiency virus (FIV) as a …

The nucleocapsid (NC) protein of HIV, which contains two CCHC-type zinc fingers
connected by a linker, is a multifunctional protein involved in many of the critical steps of the …

Background The nucleocapsid domain of Gag and mature nucleocapsid protein (NC) act as
nucleic acid chaperones and facilitate folding of nucleic acids at critical steps of retroviral …

Focused libraries of multi-substituted epidithiodiketopiperazines (ETP) were prepared and
evaluated for efficacy of inhibiting the nucleocapsid protein function of the Feline …

The nucleocapsidic protein (NC) of orthoretroviruses has been considered as a promising
target for antiretroviral drugs. Compounds, including zinc ejectors and metal derivatives …