Primary biliary cholangitis (PBC) is an autoimmune liver disease characterized by biliary
destruction, progressive cholestasis, and potentially liver cirrhosis. Patients develop a well …

The anatomical architecture of the human liver and the diversity of its immune components
endow the liver with its physiological function of immune competence. Adaptive immunity is …

Primary biliary cholangitis (PBC) has been regarded as female-predominant without
evidence of gender difference in survival. We aimed to compare the overall survival …

Primary biliary cholangitis (formerly primary biliary cirrhosis) is a rare progressive cholestatic
liver disease, whose hallmark features include a persistently elevated alkaline phosphatase …

Autoimmune liver diseases (AILDs) are potentially life-threatening chronic liver diseases
which include autoimmune hepatitis, primary biliary cholangitis, primary sclerosing …

Understanding the mechanisms that lead to autoimmunity is critical for defining potential
therapeutic pathways. In this regard there have been considerable efforts in investigating the …

Background Primary biliary cholangitis (PBC) is an autoimmune liver disease. The aetiology
of PBC remains unclear, and its pathogenesis is complex. Animal models are essential to …

Primary biliary cholangitis (PBC) is considered a model autoimmune disease due to its
signature anti‐mitochondrial antibody (AMA) autoantibody, female predominance, and …

Primary biliary cholangitis (PBC), formerly called primary biliary cirrhosis, is a chronic
cholestatic disease characterized by an autoimmune-mediated destruction of small and …

Introduction: Primary biliary cholangitis (PBC) is an autoimmune chronic disease of the liver
that can progress to cirrhosis and hepatocellular carcinoma. It affects approximately 1 in …