Factors Relating to the Biodistribution & Clearance of Nanoparticles & Their Effects on In Vivo Application

Y Wei, L Quan, C Zhou, Q Zhan - Nanomedicine, 2018 - Taylor & Francis
Nanoparticles have promising biomedical applications for drug delivery, tumor imaging and
tumor treatment. Pharmacokinetics are important for the in vivo application of nanoparticles …

Nanomicellar formulations for sustained drug delivery: strategies and underlying principles

R Trivedi, UB Kompella - Nanomedicine, 2010 - Taylor & Francis
Micellar delivery systems smaller than 100 nm can be readily prepared. While micelles allow
a great depth of tissue penetration for targeted drug delivery, they usually disintegrate …

Indocyanine green-containing nanostructure as near infrared dual-functional targeting probes for optical imaging and photothermal therapy

X Zheng, D Xing, F Zhou, B Wu… - Molecular …, 2011 - ACS Publications
Indocyanine green (ICG) is a near-infrared (NIR) imaging agent and is also an ideal light
absorber for laser-mediated photothermal therapy. This NIR dye could serve as a basis of a …

Folate-conjugated amphiphilic hyperbranched block copolymers based on Boltorn® H40, poly (l-lactide) and poly (ethylene glycol) for tumor-targeted drug delivery

M Prabaharan, JJ Grailer, S Pilla, DA Steeber, S Gong - Biomaterials, 2009 - Elsevier
Folate-conjugated amphiphilic hyperbranched block copolymer (H40–PLA-b-MPEG/PEG–
FA) with a dendritic Boltorn® H40 core, a hydrophobic poly (l-lactide)(PLA) inner shell and a …

Dendrimer-Encapsulated Camptothecins: Increased Solubility, Cellular Uptake, and Cellular Retention Affords Enhanced Anticancer Activity In vitro

MT Morgan, Y Nakanishi, DJ Kroll, AP Griset… - Cancer research, 2006 - AACR
A biocompatible polyester dendrimer composed of the natural metabolites, glycerol and
succinic acid, is described for the encapsulation of the antitumor camptothecins, 10 …

Stabilization of indocyanine green by encapsulation within micellar systems

AK Kirchherr, A Briel, K Mäder - Molecular pharmaceutics, 2009 - ACS Publications
Indocyanine green (ICG) is a fluorescence dye that is widely used for near-infrared imaging.
Application of this dye is limited by its numerous disadvantageous properties in aqueous …

Core–shell polymers: a review

RA Ramli, WA Laftah, S Hashim - Rsc Advances, 2013 - pubs.rsc.org
In this article, the basic principles of core–shell polymers (CSPs) such as definitions,
classifications and applications are critically investigated. Introduction of CSPs …

Dendritic molecular capsules for hydrophobic compounds

MT Morgan, MA Carnahan, CE Immoos… - Journal of the …, 2003 - ACS Publications
Reichardt's dye, a highly solvatochromic dye, was encapsulated within p oly (g lycerol s
uccinic a cid)([Gn]-PGLSA-OH) dendrimers to investigate the interior environment of these …

pH-sensitive unimolecular polymeric micelles: synthesis of a novel drug carrier

MC Jones, M Ranger, JC Leroux - Bioconjugate chemistry, 2003 - ACS Publications
Novel amphiphilic star-shaped polymers showing pH-sensitivity were synthesized by atom
transfer radical polymerization. These new polymers present a core− shell structure similar …

Polymeric micelles for drug targeting

A Mahmud, XB Xiong, HM Aliabadi… - Journal of drug …, 2007 - Taylor & Francis
Polymeric micelles are nano-delivery systems formed through self-assembly of amphiphilic
block copolymers in an aqueous environment. The nanoscopic dimension, stealth properties …