Feedback regulation and coordination of the main metabolism for bacterial growth and metabolic engineering for amino acid fermentation
K Shimizu, Y Matsuoka - Biotechnology Advances, 2022 - Elsevier
Living organisms such as bacteria are often exposed to continuous changes in the nutrient
availability in nature. Therefore, bacteria must constantly monitor the environmental …
availability in nature. Therefore, bacteria must constantly monitor the environmental …
RegulonDB v 10.5: tackling challenges to unify classic and high throughput knowledge of gene regulation in E. coli K-12
A Santos-Zavaleta, H Salgado… - Nucleic acids …, 2019 - academic.oup.com
RegulonDB, first published 20 years ago, is a comprehensive electronic resource about
regulation of transcription initiation of Escherichia coli K-12 with decades of knowledge from …
regulation of transcription initiation of Escherichia coli K-12 with decades of knowledge from …
Systematic identification of metabolites controlling gene expression in E. coli
Metabolism controls gene expression through allosteric interactions between metabolites
and transcription factors. These interactions are usually measured with in vitro assays, but …
and transcription factors. These interactions are usually measured with in vitro assays, but …
Metabolome and proteome analyses reveal transcriptional misregulation in glycolysis of engineered E. coli
Synthetic metabolic pathways are a burden for engineered bacteria, but the underlying
mechanisms often remain elusive. Here we show that the misregulated activity of the …
mechanisms often remain elusive. Here we show that the misregulated activity of the …
Monitoring glycolytic dynamics in single cells using a fluorescent biosensor for fructose 1, 6-bisphosphate
JN Koberstein, ML Stewart, CB Smith… - Proceedings of the …, 2022 - National Acad Sciences
Cellular metabolism is regulated over space and time to ensure that energy production is
efficiently matched with consumption. Fluorescent biosensors are useful tools for studying …
efficiently matched with consumption. Fluorescent biosensors are useful tools for studying …
Regulation of phosphate starvation-specific responses in Escherichia coli
PL Moreau - Microbiology, 2023 - microbiologyresearch.org
Toxic agents added into the medium of rapidly growing Escherichia coli induce specific
stress responses through the activation of specialized transcription factors. Each …
stress responses through the activation of specialized transcription factors. Each …
Glycolysis/gluconeogenesis specialization in microbes is driven by biochemical constraints of flux sensing
Central carbon metabolism is highly conserved across microbial species, but can catalyze
very different pathways depending on the organism and their ecological niche. Here, we …
very different pathways depending on the organism and their ecological niche. Here, we …
Deciphering the physiological response of Escherichia coli under high ATP demand
One long‐standing question in microbiology is how microbes buffer perturbations in energy
metabolism. In this study, we systematically analyzed the impact of different levels of ATP …
metabolism. In this study, we systematically analyzed the impact of different levels of ATP …
A synthetic RNA-based biosensor for fructose-1, 6-bisphosphate that reports glycolytic flux
RNA-based sensors for intracellular metabolites are a promising solution to the emerging
issue of metabolic heterogeneity. However, their development, ie, the conversion of an …
issue of metabolic heterogeneity. However, their development, ie, the conversion of an …
[图书][B] Microbial cell factories engineering for production of biomolecules
V Singh - 2021 - books.google.com
Microbial Cell Factories Engineering for Production of Biomolecules presents a compilation
of chapters written by eminent scientists worldwide. Sections cover major tools and …
of chapters written by eminent scientists worldwide. Sections cover major tools and …