Slow timescale dynamics in proteins are essential for a variety of biological functions
spanning ligand binding, enzymatic catalysis, protein folding and misfolding regulations, as …

In this review, we discuss the experimental static deuteron NMR techniques and
computational approaches most useful for the investigation of side-chain dynamics in …

The practical aspects of applying CPMG for acquisition of wideline powder patterns are
examined. It is shown that most distortions/modulations of spikelet spectra can be traced to …

Post-translationally modified (PTM) amyloid-β (Aβ) species can play an important role in
modulating Alzheimer's disease pathology. These relatively less populated modifications …

Amyloid fibril deposits observed in Alzheimer's disease comprise amyloid-β (Aβ) protein
possessing a structured hydrophobic core and a disordered N-terminal domain (residues 1 …

We have investigated microsecond to millisecond time scale dynamics in several key
hydrophobic core methyl groups of chicken villin headpiece subdomain protein (HP36) …

We employed deuterium solid‐state NMR techniques under static conditions to discern the
details of the μs–ms timescale motions in the flexible N‐terminal subdomain of Aβ1–40 …

Deuterium line shape analysis of CD3 groups has emerged as a particularly useful tool for
studying microsecond–millisecond protein motions in the solid state. The models devised so …

The feasibility of static deuterium rotating frame NMR relaxation measurements for
characterization of slow timescale motions in powder systems is demonstrated. Using a …

Methyl groups are thought to dominate the dynamics of proteins after slow collective modes
of motion freeze out in a glass-transition process. In this work we investigate methyl group …