Electroacupuncture alleviates anxiety-like behaviors induced by chronic neuropathic pain via regulating different dopamine receptors of the basolateral amygdala

M Wu, Y Chen, Z Shen, Y Zhu, S Xiao, X Zhu… - Molecular …, 2022 - Springer
Chronic pain, such as neuropathic pain, causes anxiety and other negative emotions, which
aggravates the pain sensation and increases the risk of chronic pain over time. Dopamine …

The modulatory role of dopamine receptors within the hippocampal cornu ammonis area 1 in stress-induced analgesia in an animal model of persistent inflammatory …

RA Dezfouli, PG Merdasi, M Rashvand… - Behavioural …, 2022 - journals.lww.com
The intrinsic pain inhibitory mechanisms can be activated by fear, anxiety, and stress.
Stressful experiences produce analgesia, referred to as stress-induced analgesia (SIA) …

Differences in the neural basis and transcriptomic patterns in acute and persistent pain-related anxiety-like behaviors

S Fang, Y Qin, S Yang, H Zhang, J Zheng… - Frontiers in Molecular …, 2023 - frontiersin.org
Background Both acute and persistent pain is associated with anxiety in clinical
observations, but whether the underlying neural mechanisms differ is poorly understood …

Blocking the dopaminergic receptors in the hippocampal dentate gyrus reduced the stress-induced analgesia in persistent inflammatory pain in the rat

PG Merdasi, RA Dezfouli, S Mazaheri… - Physiology & …, 2022 - Elsevier
Although the dentate gyrus (DG) as a component of the hippocampal formation has been
well known for its role in memory, various studies showed a diverse population of unique …

Blocking the dopaminergic receptors within the hippocampal dentate gyrus reduced analgesic responses induced by restraint stress in the formalin test

F Nazari-Serenjeh, M Sadeghi, R Azizbeigi… - Behavioural Brain …, 2024 - Elsevier
Previous studies have shown that various receptors, including dopamine receptors, are
expressed in the hippocampal dentate gyrus (DG). Besides, indicatively, dopamine …

Differential Roles of the D1-and D2-Like Dopamine Receptors Within the Ventral Tegmental Area in Modulating the Antinociception Induced by Forced Swim Stress in …

M Saghafi, E Danesh, R Askari, Z Mousavi… - Neurochemical …, 2024 - Springer
Several preclinical and clinical studies indicate that exposure to acute stress may decrease
pain perception and increases pain tolerance. This phenomenon is called stress-induced …

The role of dentate gyrus dopaminergic receptors in the lateral hypothalamic-induced antinociception during persistent inflammatory pain in male rats

F Torkamand, AM Aghakhani-Lobnani… - Behavioural Brain …, 2021 - Elsevier
The lateral hypothalamus (LH) is one of the key brain areas involved in pain modulation.
Also, the dentate gyrus (DG) of the hippocampus expresses various receptors, including …

Role of hippocampal orexin receptors in antinociception elicited by chemical stimulation of the lateral hypothalamus in the tail-flick test

A Zargarani, S Karimi-Haghighi… - Behavioural brain research, 2021 - Elsevier
The lateral hypothalamus (LH) orexinergic neurons project to numerous brain regions
implicated in pain perception, including the CA1 part of the hippocampal formation …

Involvement of dopaminergic system in the dentate gyrus of the hippocampus in modulating the orofacial pain-related behaviors in the rats

A Haghparast, M Yousefpour, M Rashvand… - Behavioural …, 2023 - journals.lww.com
Chemical stimulation of the lateral hypothalamus (LH) induces analgesia by forming neural
circuitries with multiple brain regions. The involvement of hippocampal dopaminergic …

D1 dopamine / mu opioid receptor interactions in operant conditioning assays of pain-depressed responding and drug-induced rate suppression, and a conditioned …

H LaCourse, L Bennett, A Falstad, F Asmus… - …, 2025 - Springer
Rationale and objectives In vivo receptor interactions vary as a function of behavioral
endpoint, with key differences between reflexive and non-reflexive measures that assess the …