Fluctuations in blood oxygenation and flow are widely used to infer brain activity during
resting-state functional magnetic resonance imaging (fMRI). However, there are strong …

Cortical neural activity is coupled to local arterial diameter and blood flow. However, which
neurons control the dynamics of cerebral arteries is not well understood. We dissected the …

Despite recent advances in our understanding of the molecular and cellular mechanisms
behind vascular conducted responses (VCRs) in systemic arterioles, we still know very little …

The human brain is possibly the most complex organ in existence. This complexity means
that it is capable of great feats, yet has ensured that it remains surprisingly poorly …

The conducted vasomotor response reflects electrical communication in the arterial wall and
the distance signals spread is regulated by three factors including resident ion channels …

Coronary blood flow is regulated to match the oxygen demand of myocytes in the heart wall.
Flow regulation is essential to meet the wide range of cardiac workload. The blood flows …

It is well established that the cerebral blood flow (CBF) shows exquisite sensitivity to
changes in the arterial blood partial pressure of CO 2 (P a, CO 2), which is reflected by an …

Objective Electrical signaling along the endothelium underlies spreading vasodilation and
blood flow control. We use mathematical modeling to determine the electrical properties of …

Key points Electrical signalling in blood vessels is important in acute and long‐term flow
regulation. As myoendothelial gap junctions (MEGJs) provide electrical contacts between …

In the rodent cerebral circulation, inward rectifying K+ (KIR) channels set resting tone and
the distance over which electrical phenomena spread along the arterial wall. The present …