In vivo bio‐safety evaluations and diagnostic/therapeutic applications of chemically designed mesoporous silica nanoparticles

Y Chen, H Chen, J Shi - Advanced Materials, 2013 - Wiley Online Library
The remarkable progress of nanotechnology and its application in biomedicine have greatly
expanded the ranges and types of biomaterials from traditional organic material‐based …

Nanoparticles in targeted cancer therapy: mesoporous silica nanoparticles entering preclinical development stage

JM Rosenholm, V Mamaeva, C Sahlgren… - Nanomedicine, 2012 - Taylor & Francis
Nanotechnology may help overcome persisting limitations of current cancer treatment and
thus contribute to the creation of more effective, safer and more affordable therapies. While …

Inorganic nanoarchitectonics for biological applications

K Ariga, Q Ji, MJ McShane, YM Lvov, A Vinu… - Chemistry of …, 2012 - ACS Publications
Inorganic structures and their assemblies play important roles in artificial materials for
biological applications. In this short review, we briefly summarize recent research on …

Nanostructured porous Si-based nanoparticles for targeted drug delivery

MA Shahbazi, B Herranz, HA Santos - Biomatter, 2012 - Taylor & Francis
One of the backbones in nanomedicine is to deliver drugs specifically to unhealthy cells.
Drug nanocarriers can cross physiological barriers and access different tissues, which after …

Hybrid Nanotrimers for Dual T1 and T2-Weighted Magnetic Resonance Imaging

K Cheng, M Yang, R Zhang, C Qin, X Su, Z Cheng - ACS nano, 2014 - ACS Publications
Development of multifunctional nanoparticle-based probes for dual T 1-and T 2-weighted
magnetic resonance imaging (MRI) could allow us to image and diagnose the tumors or …

Biodegradability of mesoporous silica nanoparticles

Y Hu, S Bai, X Wu, S Tan, Y He - Ceramics International, 2021 - Elsevier
Biodegradability significantly impacts the bioapplication of mesoporous silica nanoparticles
(MSN). In recent years, immense efforts have been made to understand and tailor the …

Improved ip drug delivery with bioadhesive nanoparticles

Y Deng, F Yang, E Cocco, E Song… - Proceedings of the …, 2016 - National Acad Sciences
The ip administration of chemotherapy in ovarian and uterine serous carcinoma patients by
biodegradable nanoparticles may represent a highly effective way to suppress peritoneal …

Multifunctional mesoporous silica nanospheres with Cleavable Gd (III) Chelates as MRI contrast agents: Synthesis, characterization, target‐specificity, and renal …

JL Vivero‐Escoto, KML Taylor‐Pashow, RC Huxford… - Small, 2011 - Wiley Online Library
Mesoporous silica nanospheres (MSNs) are a promising material for magnetic resonance
imaging (MRI) contrast agents. In this paper multifunctional MSNs with cleavable Gd (III) …

[HTML][HTML] Inorganic-organic hybrid nanomaterials for therapeutic and diagnostic imaging applications

JL Vivero-Escoto, YT Huang - International journal of molecular sciences, 2011 - mdpi.com
Nanotechnology offers outstanding potential for future biomedical applications. In particular,
due to their unique characteristics, hybrid nanomaterials have recently been investigated as …

Lanthanide-DTPA grafted silica nanoparticles as bimodal-imaging contrast agents

SLC Pinho, H Faneca, CFGC Geraldes, MH Delville… - Biomaterials, 2012 - Elsevier
The design and synthesis of a combined MRI-optical probe for bio-imaging are reported.
The materials studied join the properties of lanthanide (Ln3+) complexes and nanoparticles …