Microbiota–gut–brain axis and its therapeutic applications in neurodegenerative diseases

JS Loh, WQ Mak, LKS Tan, CX Ng, HH Chan… - … and Targeted Therapy, 2024 - nature.com
The human gastrointestinal tract is populated with a diverse microbial community. The vast
genetic and metabolic potential of the gut microbiome underpins its ubiquity in nearly every …

Current knowledge about the impact of maternal and infant nutrition on the development of the microbiota–gut–brain axis

T Cerdó, A Nieto-Ruíz, JA García-Santos… - Annual Review of …, 2023 - annualreviews.org
The prenatal and early postnatal periods are stages during which dynamic changes and the
development of the brain and gut microbiota occur, and nutrition is one of the most important …

A synbiotic preparation (SIM01) for post-acute COVID-19 syndrome in Hong Kong (RECOVERY): a randomised, double-blind, placebo-controlled trial

RI Lau, Q Su, ISF Lau, JYL Ching… - The Lancet Infectious …, 2024 - thelancet.com
Background Post-acute COVID-19 syndrome (PACS) affects over 65 million individuals
worldwide but treatment options are scarce. We aimed to assess a synbiotic preparation …

Immune memory in aging: a wide perspective covering microbiota, brain, metabolism, and epigenetics

O Bulut, G Kilic, J Domínguez-Andrés - Clinical reviews in allergy & …, 2022 - Springer
Non-specific innate and antigen-specific adaptive immunological memories are vital
evolutionary adaptations that confer long-lasting protection against a wide range of …

Antibiotic-induced gut dysbiosis and cognitive, emotional, and behavioral changes in rodents: a systematic review and meta-analysis

SS Hayer, S Hwang, JB Clayton - Frontiers in Neuroscience, 2023 - frontiersin.org
There are previous epidemiological studies reporting associations between antibiotic use
and psychiatric symptoms. Antibiotic-induced gut dysbiosis and alteration of microbiota-gut …

The effects of heavy metal exposure on brain and gut microbiota: A systematic review of animal studies

S Porru, A Esplugues, S Llop… - Environmental Pollution, 2024 - Elsevier
The gut-brain axis is a crucial interface between the central nervous system and the gut
microbiota. Recent evidence shows that exposure to environmental contaminants, such as …

Antibiotic-induced gut dysbiosis leads to activation of microglia and impairment of cholinergic gamma oscillations in the hippocampus

G Çalışkan, T French, SE Lacalle, M Del Angel… - Brain, Behavior, and …, 2022 - Elsevier
Antibiotics are widely applied for the treatment of bacterial infections, but their long-term use
may lead to gut flora dysbiosis and detrimental effects on brain physiology, behavior as well …

Mechanisms of cognitive impairment in depression. May probiotics help?

M Dobielska, NK Bartosik, KA Zyzik… - Frontiers in …, 2022 - frontiersin.org
Depression is the major cause of disability globally. Apart from lowered mood and
accompanying symptoms, it leads to cognitive impairment that altogether predicts …

[HTML][HTML] Weizmannia coagulans: an ideal probiotic for gut health

S Zhang, P Li, S Lee, Y Wang, C Tan… - Food Science and Human …, 2024 - Elsevier
Weizmannia coagulans (formerly Bacillus coagulans) is a spore-forming and lactic acid-
producing bacterium. It has recently attracted much attention from researchers and food …

Agmatine modulation of gut-brain axis alleviates dysbiosis-induced depression-like behavior in rats

S Rahangdale, P Deshmukh, S Sammeta… - European Journal of …, 2024 - Elsevier
Depression is a global health concern affecting nearly 280 million individuals. It not only
imposes a significant burden on economies and healthcare systems but also manifests …