[HTML][HTML] Targeting of tetraspanin CD81 with monoclonal antibodies and small molecules to combat cancers and viral diseases

C Bailly, X Thuru - Cancers, 2023 - mdpi.com
Simple Summary Novel therapeutic targets are needed to improve treatments of aggressive
cancers and viral diseases. Tetraspanins represent an emerging class of anticancer targets …

Recent insights on tea metabolites, their biosynthesis and chemo-preventing effects: A review

R Samynathan, M Thiruvengadam, SH Nile… - Critical reviews in …, 2023 - Taylor & Francis
Tea manufactured from the cultivated shoots of Camellia sinensis (L.) O. Kuntze is the most
commonly consumed nonalcoholic drink around the world. Tea is an agro-based …

[HTML][HTML] miR-194 inhibits the proliferation, invasion, migration, and enhances the chemosensitivity of non-small cell lung cancer cells by targeting forkhead box A1 …

X Zhu, D Li, F Yu, C Jia, J Xie, Y Ma, S Fan, H Cai… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Recent studies have implied that miRNAs may play a crucial role in tumor progression and
may be involved in the modulation of some drug resistance in cancer cells. Earlier studies …

[HTML][HTML] Megalocytivirus induces complicated fish immune response at multiple RNA levels involving mRNA, miRNA, and circRNA

Q Wu, X Ning, L Sun - International Journal of Molecular Sciences, 2021 - mdpi.com
Megalocytivirus is an important viral pathogen to many farmed fishes, including Japanese
flounder (Paralichthys olivaceus). In this study, we examined megalocytivirus-induced RNA …

Epigallocatechin gallate (EGCG) and miR-548m reduce HCV entry through repression of CD81 receptor in HCV cell models

RY Mekky, N El-Ekiaby, SA El Sobky, NM Elemam… - Archives of …, 2019 - Springer
Epigallocatechin gallate (EGCG) is the most abundant component in green tea extract, that
has powerful antioxidant and antiviral effects. It has been previously reported to inhibit HCV …

[HTML][HTML] Involvement of inflammation and its related microRNAs in hepatocellular carcinoma

K Jin, T Li, G Sánchez-Duffhues, F Zhou, L Zhang - Oncotarget, 2017 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) is the fifth most commonly diagnosed type of cancer. The
tumor inflammatory microenvironment regulates almost every step towards liver …

[HTML][HTML] The potential of epigallocatechin gallate in the chemoprevention and therapy of hepatocellular carcinoma

D Li, D Cao, Y Cui, Y Sun, J Jiang, X Cao - Frontiers in Pharmacology, 2023 - frontiersin.org
Hepatocellular carcinoma (HCC), one of the most notorious malignancies globally, has a
high fatality and poor prognosis. Though remarkable breakthroughs have been made in the …

[HTML][HTML] Expression profiles of exosomal MicroRNAs from HEV-and HCV-infected blood donors and patients: A pilot study

K McGowan, KJ Simpson, J Petrik - Viruses, 2020 - mdpi.com
Exosomes seem to play an important role in hepatits C virus (HCV) and hepatitis E virus
(HEV) infection by shielding their cargo from the host immune responses, with microRNAs …

MicroRNAs expressed during viral infection: biomarker potential and therapeutic considerations

J Louten, M Beach, K Palermino, M Weeks… - Biomarker …, 2015 - journals.sagepub.com
MicroRNAs (miRNAs) are short sequences of noncoding single-stranded RNAs that exhibit
inhibitory effects on complementary target mRNAs. Recently, it has been discovered that …

[PDF][PDF] Anti-infective potential of catechins and their derivatives against viral hepatitis

SJ Yoo, T Kwon, YS Lyoo… - Clinical and experimental …, 2018 - synapse.koreamed.org
Influenza A viruses (IAVs) are genetically diverse and variable pathogens that share various
hosts including human, swine, and domestic poultry. Interspecies and intercontinental viral …