Anticancer nanomedicines have been proven effective in mitigating the side effects of
chemotherapeutic drugs. However, challenges remain in augmenting their therapeutic …

Curative cancer therapy remains a major challenge particularly in cancers displaying
multidrug resistance (MDR). The MDR phenotype is characterized by cross-resistance to a …

Lung cancer is the common and leading cause of cancer death worldwide. The tumor
microenvironment has been recognized to be instrumental in tumorigenesis. To have a deep …

Traditional sheep grazing is the pillar industry and the main source of income for local
herders in the Inner Mongolia Autonomous Region of China. However, grazing sheep often …

γ-Glutamyltransferase (GGT), a membrane-bound enzyme, contributes to the metabolism of
glutathione (GSH), which plays a critical physiological role in protecting cells against …

γ-Glutamyl transpeptidase (GGT), a cell surface-bound protease, is associated with various
diseases including cancer. The detection of the enzyme activity is an important subject …

Biological events occur in specific cellular organelles to perform specialized roles in cells
and collaborate with other organelles. Various methods have been used to study organelle …

Abstract Avelumab (anti–PD‐L1) is an approved anticancer treatment for several indications.
The JAVELIN Gastric 100 phase III trial did not meet its primary objective of demonstrating …

Introduction: Gastric cancer (GC) is the leading cause of cancer-related death worldwide.
Despite recent advances in diagnosis and therapy, the prognosis of patients with GC is poor …

Abstract Gamma-glutamyltransferase 5 (GGT5) is a member of the gamma-glutamyl
transpeptidase gene family with the capacity of cleaving the gamma-glutamyl moiety of …