The interaction of cells within their microenvironmental niche is fundamental to cell
migration, positioning, growth and differentiation in order to form and maintain complex …

The phasor approach to fluorescence lifetime imaging has become a common method to
analyze complicated fluorescence signals from biological samples. The appeal of the …

Background Multiphoton microscopy (MPM) offers a feasible approach for the biopsy in
clinical medicine, but it has not been used in clinical applications due to the lack of efficient …

Glioblastoma (GBM) tumor is the most common primary brain malignant tumor. The precise
identification of GBM tumors is very important for diagnosis and treatment. Hyperspectral …

Two-photon imaging of endogenous fluorescence can provide physiological and metabolic
information from intact tissues. However, simultaneous imaging of multiple intrinsic …

The papillary dermis of human skin is responsible for its biomechanical properties and for
supply of epidermis with chemicals. Dermis is mainly composed of structural protein …

With the increasing use and release of plastic products, microplastics have rapidly
accumulated in ecological environments. When microplastics enter the food chain, they …

We describe the performance of a new wide area time-gated single-photon avalanche diode
(SPAD) array for phasor-FLIM, exploring the effect of gate length, gate number and signal …

The expansion of fluorescence bioimaging toward more complex systems and geometries
requires analytical tools capable of spanning widely varying timescales and length scales …

Understanding the delivery and diffusion of topically-applied drugs on human skin is of
paramount importance in both pharmaceutical and cosmetics research. This information is …