The Golgi apparatus is an essential organelle constructed by the stacking of flattened
vesicles, that is widely distributed in eukaryotic cells and is dynamically regulated during cell …

Many people in the world struggle with cancer or bacterial, parasitic, viral, Alzheimer's and
other diseases. Therefore, many scientists seek new, more effective, more selective and less …

As a crucial constituent of the endomembrane system in eukaryotic cells, the Golgi
apparatus serves as a major transport hub for intracellular macromolecular transport. Its …

The development of drug resistance and severe side-effects has reduced the clinical efficacy
of the existing anti-cancer drugs available in the market. Thus, there is always a constant …

Inflammation is a complex phenomenon necessary in human defense mechanisms but also
involved in the development of some human diseases. The discovery of cyclooxygenase-2 …

Fluorescence imaging has become crucial in cell biology, mainly because of its ability to
visualize the cells at the molecular level. Subcellular organs including mitochondria …

Cyclooxygenase-2 (COX-2) is an enzyme overexpressed in most types of cancers and has
been used for an excellent targetable biomarker. Celecoxib is an effective inhibitor of COX …

2-Alkynylbenzamides underwent different reaction pathways when allowed to react under
PdI2-catalyzed oxidative carbonylation conditions, depending on the nature of the external …

Benzo-fused γ-lactam rings such as isoindolin-2-ones and 2-oxindoles are part of the
structure of many pharmaceutically active molecules. They can be often synthesized by …

Cyclooxygenase-2 (COX-2) fluorescent probes are promising tools for early diagnosis of
cancer. Traditionally, COX-2 probes were designed by connecting two parts, a fluorophore …