Haematopoietic stem cells (HSCs) are a self-renewing population of cells that continuously
replenish all blood and immune cells during the lifetime of an individual,. HSCs are used …

As an alternative to perfluorooctanesulfonate (PFOS), 6: 2 chlorinated polyfluorinated ether
sulfonate (commercial name: F-53B) has been used as a mist suppressant in Chinese …

The vertebrate body forms in an anterior-to-posterior progression, driven by a population of
undifferentiated cells at the posterior-most end of the embryo. Recent studies have …

A~ 1 Mb inversion polymorphism exists within the 17q21. 31 locus of the human genome as
direct (H1) and inverted (H2) haplotype clades. This inversion region demonstrates high …

One of the biggest challenges in tumour research is the possibility to reprogram cancer cells
towards less aggressive phenotypes. In this study, we reprogrammed primary Glioblastoma …

Hematopoietic stem cells (HSC s) require multiple molecular inputs for proper specification,
including activity of the Notch signaling pathway. A requirement for the Notch1 and …

Traumatic spinal cord injury (SCI) is a leading cause of permanent neurologic disabilities in
young adults. Functional impairments after SCI are substantially attributed to the progressive …

Social living animals need to adjust the expression of their behavior to their status within the
group and to changes in social context and this ability (social plasticity) has an impact on …

Cell behaviour and function is determined through the interactions of a multitude of
molecules working in concert. To observe these molecular dynamics, biophysical studies …

All mature blood cell types in the adult animal arise from hematopoietic stem and progenitor
cells (HSPCs). However, the developmental cues regulating HSPC ontogeny are …