Topography-mediated immunomodulation in osseointegration; Ally or Enemy

S Shirazi, S Ravindran, LF Cooper - Biomaterials, 2022 - Elsevier
Osteoimmunology is at full display during endosseous implant osseointegration. Bone
formation, maintenance and resorption at the implant surface is a result of bidirectional and …

The pyroptotic role of Caspase-3/GSDME signalling pathway among various cancer: A Review

AA Bhat, R Thapa, O Afzal, N Agrawal… - International journal of …, 2023 - Elsevier
Cytotoxic drugs have long been recognised to kill cancer cells through apoptosis. According
to a current study, pyroptosis inhibits cell proliferation and shrinks tumors. Pyroptosis and …

Gasdermin e: A prospective target for therapy of diseases

XX Liao, YZ Dai, YZ Zhao, K Nie - Frontiers in Pharmacology, 2022 - frontiersin.org
Gasdermin E (GSDME) is a member of the gasdermin protein family, which mediates
programmed cell death including apoptosis and pyroptosis. Recently, it was suggested that …

Pyroptosis in periodontitis: From the intricate interaction with apoptosis, NETosis, and necroptosis to the therapeutic prospects

X Xu, T Zhang, X Xia, Y Yin, S Yang, D Ai… - Frontiers in Cellular …, 2022 - frontiersin.org
Periodontitis is highly prevalent worldwide. It is characterized by periodontal attachment and
alveolar bone destruction, which not only leads to tooth loss but also results in the …

In vivo studies of medical implants for maxillofacial surgery produced from nanostructured titanium

AA Matchin, EV Nosov, AA Stadnikov… - ACS Biomaterials …, 2023 - ACS Publications
This paper presents the results of comprehensive in vivo studies into the osseointegration
behavior of medical implants for maxillofacial surgery produced from nanostructured grade 4 …

Peri-implantitis Diagnosis and Prognosis Using Biomarkers: A Systematic Literature Review.

V Pliavga, G Peceliunaite, P Daugela… - … Journal of Oral & …, 2023 - search.ebscohost.com
Purpose: To summarize the latest scientific literature regarding the concentrations of
biomarkers in saliva and peri-implant crevicular fluid (PICF) of healthy implant (HI) patients …

细胞焦亡相关蛋白在钽融合器松动周围组织中的表达及意义

龙智生, 扶流祥, 龚飞鹏, 温家宾, 邓颖, 闵欢, 邓专… - 中国组织工程研究, 2023 - cjter.com
摘要背景: 钽融合器植入椎间隙后如何影响其周围细胞最终导致骨溶解, 发生无菌性松动,
其机制有待阐明. 目的: 探索细胞焦亡在钽所致椎间骨溶解中的作用. 方法: 选择2015 年1 …

The Critical Role of Pyroptosis in Peri-Implantitis

L Chen, Z Tang, L Fu, Y Xie, J Xu, H Xia… - Journal of …, 2024 - Taylor & Francis
Background Peri-implantitis (PI) is a prevalent complication of implant treatment. Pyroptosis,
a distinctive inflammatory programmed cell death, is crucial to the pathophysiology of PI …

Caspase‐3/GSDME‐mediated pyroptosis leads to osteogenic dysfunction of osteoblast‐like cells

Z Wu, Q Ding, M Yue, X Zhang, D Han… - Oral Diseases, 2024 - Wiley Online Library
Objective Cell pyroptosis is implicated in progressive bone loss in dental inflammatory
diseases. We induced caspase‐3/Gasdermin E (GSDME)‐mediated pyroptosis in osteoblast …

Anti‐Apoptotic and Pro‐Apoptotic Bcl‐2 Family Proteins in Peri‐Implant Diseases

D Yilmaz, M Gürsoy, UK Gürsoy - Clinical Oral Implants …, 2023 - Wiley Online Library
Objectives Intrinsic apoptosis, which is regulated by Bcl‐2 family proteins, has an important
role in chronic inflammatory diseases. The aim of the study was to identify the tissue levels …