Obesity II: establishing causal links between chemical exposures and obesity

JJ Heindel, S Howard, K Agay-Shay, JP Arrebola… - Biochemical …, 2022 - Elsevier
Obesity is a multifactorial disease with both genetic and environmental components. The
prevailing view is that obesity results from an imbalance between energy intake and …

[HTML][HTML] Environmental obesogens and their impact on susceptibility to obesity: new mechanisms and chemicals

RJ Egusquiza, B Blumberg - Endocrinology, 2020 - academic.oup.com
The incidence of obesity has reached an all-time high, and this increase is observed
worldwide. There is a growing need to understand all the factors that contribute to obesity to …

Epigenetic transgenerational inheritance of obesity susceptibility

SE King, MK Skinner - Trends in Endocrinology & Metabolism, 2020 - cell.com
The prevalence of obesity and associated diseases has reached pandemic levels. Obesity is
often associated with overnutrition and a sedentary lifestyle, but clearly other factors also …

Obesogens: How they are identified and molecular mechanisms underlying their action

N Mohajer, CY Du, C Checkcinco… - Frontiers in …, 2021 - frontiersin.org
Adult and childhood obesity have reached pandemic level proportions. The idea that caloric
excess and insufficient levels of physical activity leads to obesity is a commonly accepted …

The role of persistent organic pollutants in obesity: a review of laboratory and epidemiological studies

J Aaseth, D Javorac, AB Djordjevic, Z Bulat, AV Skalny… - Toxics, 2022 - mdpi.com
Persistent organic pollutants (POPs) are considered as potential obesogens that may affect
adipose tissue development and functioning, thus promoting obesity. However, various …

Grandmaternal perinatal serum DDT in relation to granddaughter early menarche and adult obesity: three generations in the child health and development studies …

PM Cirillo, MA La Merrill, NY Krigbaum… - … , Biomarkers & Prevention, 2021 - AACR
Abstract Background: Serum DDTs during or just after pregnancy were associated with
breast cancer in mothers (F0), and with breast cancer, mammographic density, and obesity …

Epigenetic transgenerational inheritance of the effects of obesogen exposure

N Mohajer, EM Joloya, J Seo, T Shioda… - Frontiers in …, 2021 - frontiersin.org
Obesity and metabolic disorders have become a worldwide pandemic affecting millions of
people. Although obesity is a multifaceted disease, there is growing evidence supporting the …

Generational stability of epigenetic transgenerational inheritance facilitates adaptation and evolution

A Korolenko, MK Skinner - Epigenetics, 2024 - Taylor & Francis
The epigenome and epigenetic inheritance were not included in the original modern
synthesis theory or more recent extended evolutionary synthesis of evolution. In a broad …

A systematic scientometric review of paternal inheritance of acquired metabolic traits

L Crisóstomo, PF Oliveira, MG Alves - BMC biology, 2023 - Springer
Background The concept of the inheritance of acquired traits, a foundational principle of
Lamarck's evolutionary theory, has garnered renewed attention in recent years. Evidence for …

[HTML][HTML] Focus: Climate Change and Environmental Health: Epigenetic Inheritance and Transgenerational Environmental Justice

AA Korolenko, SE Noll, MK Skinner - The Yale Journal of Biology …, 2023 - ncbi.nlm.nih.gov
Many chemicals and toxicants are released into our ecosystem and environment every day,
which can cause harmful effects on human populations. Agricultural compounds are used in …