Both type 1 and type 2 diabetes adversely affect the microvasculature in multiple organs.
Our understanding of the genesis of this injury and of potential interventions to prevent, limit …

The pathogenesis of diabetic neuropathy is complex, and various pathogenic pathways
have been proposed. A better understanding of the pathophysiology is warranted for …

Diabetes mellitus (DM) is a huge global health issue and one of the most studied diseases,
with a large global prevalence. Oxidative stress is a cytotoxic consequence of the excessive …

Peripheral neuropathy (PN) is a common disease affecting about 5% of the general
population after the age of 50. Causes of PN are numerous and include genetic, diabetes …

AIM: To compare patients with advanced stage endometriosis with control patients without
endometriosis with respect to serum Copper (Cu) and Ceruloplasmin (Cp) levels and …

Prolidase is a metal-dependent peptidase specialized in the cleavage of dipeptides
containing proline or hydroxyproline on their C-termini. Prolidase homologues are found in …

Oxidative stress is implicated in the pathogenesis of experimental diabetic neuropathy, but
prospective studies in diabetic patients are lacking. We aimed to evaluate whether the …

Urinary exosomes (UE) are nanovesicles released by every epithelial cell facing the urinary
space and they are considered a promising source of molecular markers for renal …

Association of oxidative stress and serum prolidase activity (SPA) has been reported in
many chronic diseases. The study was aimed at evaluating the correlation of glucose and …

Prolidase deficiency has been related to mental retardation and oxidative stress. The study
aimed to observe plasma prolidase activity (PPA), total oxidant status (TOS), total antioxidant …