Lactate is the main product generated at the end of anaerobic glycolysis or during the
Warburg effect and its role as an active signalling molecule is increasingly recognised …

Bloodstream infection is a major public health concern associated with high mortality and
high healthcare costs worldwide. Bacteremia can trigger fatal sepsis whose prevention …

Staphylococcus aureus is a leading cause of biofilm-associated prosthetic joint infection
(PJI), resulting in considerable disability and prolonged treatment. It is known that host …

Unique coumarin conjugates with thiazolidinone as novel structural antibacterial modulators
were exploited to combat the lethal multidrug-resistant bacterial infections. Bioactivity …

Nanoparticles (NPs) have biological activities like antibacterial, antifungal, drug delivery,
immunomodulation and antitumor activities. The aim of the current study was to investigate …

Two-dimensional molybdenum disulfide (MoS2) based nanosheets functionalized or loaded
with an antimicrobial agent have recently attracted attention as highly efficient antibacterial …

With the soaring of bacterial infection and drug resistance, it is imperative to exploit new
efficient antibacterial agents. This work constructed a series of unique phenylhydrazone …

An unprecedented amount of fungal and fungal-like infections has recently brought about
some of the most severe die-offs and extinctions due to fungal drug resistance. Aimed to …

A series of 2-aminothiazole sulfanilamide oximes were developed as new membrane active
antibacterial agents to conquer the microbial infection. Benzoyl derivative 10c was …

Comprehensive Summary A class of new potential antibacterial agents with distinctive
pyrimidinone benzimidazole skeleton was developed through nucleophilic substitution and …