Reactive oxygen species: Role in carcinogenesis, cancer cell signaling and tumor progression

FL Sarmiento-Salinas, A Perez-Gonzalez… - Life Sciences, 2021 - Elsevier
Cancer is one of the major causes of death in the world and its global burden is expected to
continue increasing. In several types of cancers, reactive oxygen species (ROS) have been …

Nutraceuticals and cancer: Potential for natural polyphenols

J Maiuolo, M Gliozzi, C Carresi, V Musolino… - Nutrients, 2021 - mdpi.com
Cancer is one of the leading causes of death globally, associated with multifactorial
pathophysiological components. In particular, genetic mutations, infection or inflammation …

Antioxidants in brain tumors: current therapeutic significance and future prospects

X Qi, SK Jha, NK Jha, S Dewanjee, A Dey, R Deka… - Molecular Cancer, 2022 - Springer
Brain cancer is regarded among the deadliest forms of cancer worldwide. The distinct tumor
microenvironment and inherent characteristics of brain tumor cells virtually render them …

From fighting critters to saving lives: polyphenols in plant defense and human health

A Stiller, K Garrison, K Gurdyumov, J Kenner… - International journal of …, 2021 - mdpi.com
Polyphenols, such as flavonoids and phenolic acids, are a group of specialized metabolites
in plants that largely aid in plant defense by deterring biotic stressors and alleviating abiotic …

Mutant P53 in the formation and progression of the tumor microenvironment: friend or foe

ER Asl, D Rostamzadeh, PHG Duijf, S Mafi, B Mansoori… - Life sciences, 2023 - Elsevier
TP53 is the most frequently mutated gene in human cancer. It encodes the tumor suppressor
protein p53, which suppresses tumorigenesis by acting as a critical transcription factor that …

[HTML][HTML] Optimizing CRISPR/Cas9 precision: Mitigating off-target effects for safe integration with photodynamic and stem cell therapies in cancer treatment

JPJ Merlin, H Abrahamse - Biomedicine & Pharmacotherapy, 2024 - Elsevier
CRISPR/Cas9 precision genome editing has revolutionized cancer treatment by introducing
specific alterations to the cancer genome. But the therapeutic potential of CRISPR/Cas9 is …

Combined lifestyle, mental health, and mortality in US cancer survivors: a national cohort study

Z Liu, C Wang, Y Zhang, H Zhu - Journal of Translational Medicine, 2022 - Springer
Background Adopting healthy lifestyles and staying mentally health are two cost-effective
modifiable strategies that cancer survivors can implement in self-management. We aimed to …

Understanding the complex milieu of epithelial-mesenchymal transition in cancer metastasis: new insight into the roles of transcription factors

SO Imodoye, KA Adedokun, AO Muhammed… - Frontiers in …, 2021 - frontiersin.org
Epithelial-mesenchymal transition (EMT) is a physiological program during which polarised,
immobile epithelial cells lose connection with their neighbours and are converted to …

Genistein and procyanidin B2 reduce carcinogen-induced reactive oxygen species and DNA damage through the activation of Nrf2/ARE cell signaling in Bronchial …

TL Suraweera, JPJ Merlin, G Dellaire, Z Xu… - International Journal of …, 2023 - mdpi.com
Cancer is one of the leading causes of death worldwide. Chemotherapy and radiation
therapy are currently providing the basis for cancer therapies, although both are associated …

Antioxidants in traditional mexican medicine and their applications as antitumor treatments

KM Soto, JJ Pérez Bueno, ML Mendoza López… - Pharmaceuticals, 2023 - mdpi.com
Traditional medicine in Latin America and mainly in Mexico represents an essential
alternative for treating different diseases. The use of plants as medicine is the product of a …