Lichens are symbiotic associations between fungi and a photosynthetic alga and/or
cyanobacteria. Lichenized fungi have been found to produce a wide array of secondary …

This article provides an overview of approximately 300 secondary metabolites with inhibitory
activity against protein tyrosine phosphatase 1B (PTP1B), which were isolated from various …

Among the various compounds of natural origin, usnic acid (UA) is one of the best studied. It
has several pharmacological activities, standing out as an antimicrobial, antitumor, antiviral …

To identify the biosynthetic gene cluster responsible for the biosynthesis of the polyketide
usnic acid we carried out the de novo genome sequencing of the fungal partner of Cladonia …

Usnic acid (UA) is a commercially available lichen metabolite. Its biological activity is
diverse. Its broad occurrence in various lichen species, simple isolation procedure, and high …

Plant-based medicines are the most appropriate and safe to be used as alternative
medicines compared to synthetic drugs. Since time immemorial, medicinal plants have …

Usnic acid is a unique polyketide produced by lichens. To characterize usnic acid
biosynthesis, the transcriptome of the usnic-acid-producing lichen-forming fungus …

Using ultraviolet spectrophotometry, the solubility of (+)-usnic acid in water, ethanol,
acetone, ethyl acetate and n-hexane were measured at temperatures from (278.15 to …

During the years, many usnic acid (UA) conjugates have been synthesized to obtain potent
endowed with biological properties. Since (S)-UA is less abundant in nature than (R) …

We report for the first time the in vitro effect of Potassium Salt, derived from Usnic Acid (PS-
UA), isolated from the lichen Cladonia substellata Vanio, on couples of Schistosoma …