A critical review on the particle generation and other applications of rapid expansion of supercritical solution

R Kumar, AK Thakur, N Banerjee… - International Journal of …, 2021 - Elsevier
The novel particle generation processes of Active Pharmaceutical Ingredient (API)/drug
have been extensively explored in recent decades due to their wide-range applications in …

Particle synthesis by rapid expansion of supercritical solutions (RESS): Current state, further perspectives and needs

M Türk - Journal of Aerosol Science, 2022 - Elsevier
The application of supercritical fluids in particle formation processes has attracted great
attention due to numerous advantages over classical size reduction technologies. These …

Experimental evaluation and thermodynamic analysis of Febuxostat solubility in supercritical solvent

MAS Abourehab, S Alshehri, RM Alzhrani… - Journal of Molecular …, 2022 - Elsevier
In order to develop novel supercritical carbon dioxide (scCO 2)-based processes in the
pharmaceutical industry, it is necessary to determine the solubility of drugs in scCO2. In the …

Particle size design of acetaminophen using supercritical carbon dioxide to improve drug delivery: Experimental and modeling

H Bagheri, H Hashemipour, E Rahimpour… - Journal of …, 2021 - Elsevier
In this communication, micronized acetaminophen particles are investigated using the rapid
expansion of the supercritical solution (RESS) process. According to the obtained results …

Study of hyoscine solubility in scCO2: Experimental measurement and thermodynamic modeling

U Hani, HE Alosaimi, B Huwaimel, TN Alharby… - Journal of Molecular …, 2023 - Elsevier
In this research, solubility of Hyoscine, as the most well-known drugs used to relieve
spasmodic abdominal pain, in supercritical carbon dioxide (scCO 2) was determined at 170 …

Supercritical fluid-assisted fabrication of C-doped Co3O4 nanoparticles based on polymer-coated metal salt nanoreactors for efficient enzyme-mimicking and …

ZW Kang, JY Zhang, ZZ Li, RK Kankala, SB Wang… - Nano Research, 2023 - Springer
Nanomaterials doped with non-metallic C have attracted tremendous attention as potential
nano-artificial enzymes due to their ability to change the energy band structure to improve …

Advanced technology using supercritical fluid for particle production in pharmaceutical continuous manufacturing

ES Ha, HT Kang, H Park, S Kim, MS Kim - Journal of Pharmaceutical …, 2023 - Springer
Background In the pharmaceutical industry, supercritical fluid (SCF), particularly supercritical
carbon dioxide (SC-CO2), can be utilized as a solvent, extractant, liquid expander …

Supercritical fluid-assisted fabrication of Pt-modified cerium oxide nanozyme based on polymer nanoreactors for peroxidase-like and glucose detection characteristics

ZW Kang, ZZ Li, RK Kankala, SB Wang… - The Journal of …, 2023 - Elsevier
To address the key problems of natural proteases in terms of stability, transportation and
storage, this work demonstrates the preparation of a Pt/CeO 2 precursor based nanozymes …

Disulfiram: A Food and Drug Administration-approved multifunctional role in synergistically drug delivery systems for tumor treatment

L Xu, Y Sun, Y Li, J Sun, Y Guo, Q Shen, Q Wei… - International Journal of …, 2022 - Elsevier
Disulfiram (DSF), a Food and Drug Administration (FDA)-approved drug for the treatment of
alcoholism, has been found to have antitumor activity. DSF showed better antitumor …

Development of highly stable ICG-polymeric nanoparticles with ultra-high entrapment efficiency using supercritical antisolvent (SAS)-combined solution casting …

PY Xu, RK Kankala, SB Wang, AZ Chen - International Journal of …, 2022 - Elsevier
Indocyanine green (ICG), a water-soluble near-infrared (NIR) photosensitizer, has been
enormously regarded in tumor diagnosis and phototherapy. Although tremendous progress …