The oyster immunity

L Wang, X Song, L Song - Developmental & Comparative Immunology, 2018 - Elsevier
Oysters, the common name for a number of different bivalve molluscs, are the worldwide
aquaculture species and also play vital roles in the function of ecosystem. As invertebrate …

The neuroendocrine-immune regulation in response to environmental stress in marine bivalves

Z Liu, M Li, Q Yi, L Wang, L Song - Frontiers in Physiology, 2018 - frontiersin.org
Marine bivalves, which include many species worldwide, from intertidal zones to
hydrothermal vents and cold seeps, are important components of the ecosystem and …

Postoperative pain—from mechanisms to treatment

EM Pogatzki-Zahn, D Segelcke, SA Schug - Pain reports, 2017 - journals.lww.com
Objectives: This review presents and discusses basic science findings and scientific
evidence generated within the last 2 decades in the field of acute postoperative pain …

Drugging the pain epigenome

E Niederberger, E Resch, MJ Parnham… - Nature Reviews …, 2017 - nature.com
More than 20% of adults worldwide experience different types of chronic pain, which are
frequently associated with several comorbidities and a decrease in quality of life. Several …

Dual BET/HDAC inhibition to relieve neuropathic pain: recent advances, perspectives, and future opportunities

MN Romanelli, V Borgonetti, N Galeotti - Pharmacological Research, 2021 - Elsevier
Despite the intense research on developing new therapies for neuropathic pain states,
available treatments have limited efficacy and unfavorable safety profiles. Epigenetic …

Hippocampal glutamatergic synapses impairment mediated novel-object recognition dysfunction in rats with neuropathic pain

B Xiong, W Zhang, L Zhang, X Huang, W Zhou, Q Zou… - Pain, 2020 - journals.lww.com
Cognitive impairment is one of the most common complications associated with chronic
pain. Almost 20% of chronic pain patients suffer from cognitive impairment, which may …

The epigenetics of neuropathic pain: A systematic update

G Pethő, B Kántás, Á Horváth, E Pintér - International Journal of …, 2023 - mdpi.com
Epigenetics deals with alterations to the gene expression that occur without change in the
nucleotide sequence in the DNA. Various covalent modifications of the DNA and/or the …

Normalizing HDAC2 levels in the spinal cord alleviates thermal and mechanical hyperalgesia after peripheral nerve injury and promotes GAD65 and KCC2 …

B Ouyang, D Chen, X Hou, T Wang, J Wang… - Frontiers in …, 2019 - frontiersin.org
Neuropathic pain is a worldwide health concern with poor treatment outcomes.
Accumulating evidence suggests that histone hypoacetylation is involved in development …

Prenatal nicotine exposure impairs the proliferation of neuronal progenitors, leading to fewer glutamatergic neurons in the medial prefrontal cortex

Y Aoyama, K Toriumi, A Mouri, T Hattori… - …, 2016 - nature.com
Cigarette smoking during pregnancy is associated with various disabilities in the offspring
such as attention deficit/hyperactivity disorder, learning disabilities, and persistent anxiety …

Developing modern pain therapies

J Manion, MA Waller, T Clark, JN Massingham… - Frontiers in …, 2019 - frontiersin.org
Chronic pain afflicts as much as 50% of the population at any given time but our methods to
address pain remain limited, ineffective and addictive. In order to develop new therapies an …