Multidrug resistant bacteria are a global threat for human and animal health. However, they
are only part of the problem of antibiotic failure. Another bacterial strategy that contributes to …

Phage therapy, long overshadowed by chemical antibiotics, is garnering renewed interest in
Western medicine. This stems from the rise in frequency of multi-drug-resistant bacterial …

Antibiotic resistance is a major public health challenge worldwide, whose implications for
global health might be devastating if novel antibacterial strategies are not quickly …

Bacteriophages are ubiquitous viral predators that have primarily been studied using fast-
growing laboratory cultures of their bacterial hosts. However, microbial life in nature is …

Background. Increasing antibiotic resistance warrants therapeutic alternatives. Here we
investigated the efficacy of bacteriophage-therapy (phage) alone or combined with …

The global rise of antibiotic resistance in bacterial pathogens and the waning efficacy of
antibiotics urge consideration of alternative antimicrobial strategies. Phage therapy is a …

Highlights•Interaction of phages and biofilm cells depends on phage-host characteristics
and biofilm structure.•Biofilm features (eg matrix, cell metabolic state, resistant variants) …

Soon after their discovery in the early 20th century, bacteriophages were recognized to have
great potential as antimicrobial agents, a potential that has yet to be fully realized. The …

With the emergence of multidrug-resistant and extensively drug-resistant bacterial
pathogens, phage therapy and other alternative or additional therapeutic modalities are …

Species in the genus Pseudomonas thrive in a diverse set of ecological niches and include
crucial pathogens, such as the human pathogen Pseudomonas aeruginosa and the plant …