Traumatic brain injury: progress and challenges in prevention, clinical care, and research
Executive summary Traumatic brain injury (TBI) has the highest incidence of all common
neurological disorders, and poses a substantial public health burden. TBI is increasingly …
neurological disorders, and poses a substantial public health burden. TBI is increasingly …
Recovery from disorders of consciousness: mechanisms, prognosis and emerging therapies
Substantial progress has been made over the past two decades in detecting, predicting and
promoting recovery of consciousness in patients with disorders of consciousness (DoC) …
promoting recovery of consciousness in patients with disorders of consciousness (DoC) …
Traumatic brain injury: integrated approaches to improve prevention, clinical care, and research
Executive summary A concerted effort to tackle the global health problem posed by traumatic
brain injury (TBI) is long overdue. TBI is a public health challenge of vast, but insufficiently …
brain injury (TBI) is long overdue. TBI is a public health challenge of vast, but insufficiently …
Dopaminergic brainstem disconnection is common to pharmacological and pathological consciousness perturbation
LRB Spindler, AI Luppi, RM Adapa… - Proceedings of the …, 2021 - National Acad Sciences
Clinical research into consciousness has long focused on cortical macroscopic networks
and their disruption in pathological or pharmacological consciousness perturbation. Despite …
and their disruption in pathological or pharmacological consciousness perturbation. Despite …
The Human Connectome Project and beyond: initial applications of 300 mT/m gradients
The engineering of a 3 T human MRI scanner equipped with 300 mT/m gradients–the
strongest gradients ever built for an in vivo human MRI scanner–was a major component of …
strongest gradients ever built for an in vivo human MRI scanner–was a major component of …
Cortically projecting basal forebrain parvalbumin neurons regulate cortical gamma band oscillations
Cortical gamma band oscillations (GBO, 30–80 Hz, typically∼ 40 Hz) are involved in higher
cognitive functions such as feature binding, attention, and working memory. GBO …
cognitive functions such as feature binding, attention, and working memory. GBO …
The curing coma campaign: framing initial scientific challenges—proceedings of the first curing coma campaign scientific advisory council meeting
Coma and disordered consciousness are common manifestations of acute neurological
conditions and are among the most pervasive and challenging aspects of treatment in …
conditions and are among the most pervasive and challenging aspects of treatment in …
The structural connectivity mapping of the intralaminar thalamic nuclei
VJ Kumar, K Scheffler, W Grodd - Scientific Reports, 2023 - nature.com
The intralaminar nuclei of the thalamus play a pivotal role in awareness, conscious
experience, arousal, sleep, vigilance, as well as in cognitive, sensory, and sexual …
experience, arousal, sleep, vigilance, as well as in cognitive, sensory, and sexual …
Mechanisms underlying disorders of consciousness: bridging gaps to move toward an integrated translational science
Aim In order to successfully detect, classify, prognosticate, and develop targeted therapies
for patients with disorders of consciousness (DOC), it is crucial to improve our mechanistic …
for patients with disorders of consciousness (DOC), it is crucial to improve our mechanistic …
Injury patterns associated with cognitive motor dissociation
In unconscious appearing patients with acute brain injury, wilful brain activation to motor
commands without behavioural signs of command following, known as cognitive motor …
commands without behavioural signs of command following, known as cognitive motor …