A state-of-the-art review on the recent advances of niosomes as a targeted drug delivery system

S Yasamineh, P Yasamineh, HG Kalajahi… - International journal of …, 2022 - Elsevier
The buildup of nonionic surfactants in the aqueous environment produces niosomes. The
usage of niosomes is becoming increasingly frequent due to their sustainability, low cost of …

Recent green chemistry approaches for pyrimidine derivatives as a potential anti-cancer agent: An overview (2013–2023)

K Kajal, R Shakya, M Rashid, V Nigam… - Sustainable Chemistry …, 2024 - Elsevier
The widespread scrutiny of orthodox synthetic techniques for the fabrication of nitrogen-
embracing heteroatom segments has shifted scholar's focus to innovative environmentally …

Chitosan surface-modified PLGA nanoparticles loaded with cranberry powder extract as a potential oral delivery platform for targeting colon cancer cells

MM Mostafa, MM Amin, MY Zakaria, MA Hussein… - Pharmaceutics, 2023 - mdpi.com
Nutraceutical cranberry powder extract (CBPE) has distinct polyphenols inhibiting colon
cancer growth and proliferation. However, its oral therapeutic efficacy is hindered because …

Ultra-deformable free fatty acid based nano-carriers for topical delivery of Luteolin: A potential paradigm for management of Methicillin-Resistant Staphylococcus …

MY Zakaria, WA Eraqi, SA Mohamed - International Journal of …, 2023 - Elsevier
The incidences of antimicrobial resistance in particular, Methicillin-Resistant Staphylococcus
aureus (MRSA) have increased during the last two decades. However, conventional dosage …

Design and synthesis of new trimethoxylphenyl-linked combretastatin analogues loaded on diamond nanoparticles as a panel for ameliorated solubility and …

I Zaki, AMY Moustafa, BY Beshay… - Journal of enzyme …, 2022 - Taylor & Francis
A new series of vinyl amide-, imidazolone-, and triazinone-linked combretastatin A-4
analogues have been designed and synthesised. These compounds have been evaluated …

Design and statistical optimisation of emulsomal nanoparticles for improved anti-SARS-CoV-2 activity of N-(5-nitrothiazol-2-yl)-carboxamido candidates: in vitro and in …

AA Al-Karmalawy, DS El-Gamil… - Journal of Enzyme …, 2023 - Taylor & Francis
In this article, emulsomes (EMLs) were fabricated to encapsulate the N-(5-nitrothiazol-2-yl)-
carboxamido derivatives (3a–3g) in an attempt to improve their biological availability and …

Novel pyridine bearing pentose moiety-based anticancer agents: Design, synthesis, radioiodination and bioassessments

MM Mehany, OA Hammam, AA Selim, GH Sayed… - Scientific Reports, 2024 - nature.com
Pyridine compounds are one of the most important heterocyclic derivatives showing wide
ranges in biological and pharmacological activities. Green chemistry eliminates or reduces …

Boosting the anti MERS-CoV activity and oral bioavailability of resveratrol via PEG-stabilized emulsomal nano-carrier: factorial design, in-vitro and in-vivo …

MY Zakaria, I Zaki, M Alhomrani, AS Alamri… - Drug Delivery, 2022 - Taylor & Francis
Resveratrol (RSV) is a phytoceutical polyphenolic compound exhibiting a well evidenced
wide range of therapeutic activities. Unfortunately, its diminished aqueous solubility and …

Experimental design of D-α-tocopherol polyethylene glycol 1000 succinate stabilized bile salt based Nano-vesicles for improved cytotoxicity and bioavailability of …

AA Elmaaty, AA Al‐Karmalawy, MS Nafie… - International Journal of …, 2023 - Elsevier
Nowadays, conventional anticancer therapy suffers many pitfalls, including drastic side
effects and limited therapeutic efficacy resulting from diminished oral bioavailability. So, in …

Phytomedicinal flavonoid loaded phospholipid sheathed lipidic nano-carriers as a platform with boosted oral anti-mycobacterium activity

RE Elnady, MM Amin, MY Zakaria - Journal of Drug Delivery Science and …, 2023 - Elsevier
Naringenin (NAR) has recently been proven to exert antituberculosis activity (anti-TB);
however, because of its poor solubility and limited oral bioavailability, this is not enough for …