Epidemiology and surveillance of autoimmune hepatitis in Asia

T Katsumi, Y Ueno - Liver International, 2022 - Wiley Online Library
Autoimmune hepatitis (AIH) is a chronic inflammatory liver disease that mainly injures the
hepatocytes. The autoimmune disease might be involved in its aetiology, but this remains to …

HLA, gut microbiome and hepatic autoimmunity

B Terziroli Beretta-Piccoli, G Mieli-Vergani… - Frontiers in …, 2022 - frontiersin.org
Genetic susceptibility to autoimmune liver diseases is conferred mainly by polymorphisms of
genes encoding for the human leukocyte antigens (HLA). The strongest predisposition to …

The Asian Pacific Association for the Study of the Liver clinical practice guidance: the diagnosis and management of patients with autoimmune hepatitis

G Wang, A Tanaka, H Zhao, J Jia, X Ma… - Hepatology …, 2021 - Springer
Guiqiang Wang1, 18· Atsushi Tanaka2· Hong Zhao1, 1 8· Jidong Jia3· Xiong Ma4· Kenichi
Harada5· Fu‑Sheng Wang6· Lai Wei7· Qixia Wang4· Ying Sun6· Yuan Hong1· Huiying …

Autoimmune diseases and 8.1 ancestral haplotype: an update

CM Gambino, A Aiello, G Accardi, C Caruso… - Hla, 2018 - Wiley Online Library
The aim of the present review is to provide an update of the current research into the
pathogenesis of autoimmune diseases associated with 8.1 ancestral haplotype. This is a …

Autoimmune hepatitis in the Asia-Pacific area

QX Wang, L Yan, X Ma - Journal of Clinical and Translational …, 2017 - pmc.ncbi.nlm.nih.gov
Autoimmune hepatitis has been considered as a relatively rare immunological liver disease,
especially in the Asia-Pacific area. Although the diagnosis criteria and immunosuppressive …

Recognizing dysfunctional innate and adaptive immune responses contributing to liver damage in patients with cirrhosis

R Goel, CE Eapen - Journal of Clinical and Experimental Hepatology, 2022 - Elsevier
The human host immune system wards off attacks by enemies such as viruses by mounting
an inflammatory response which may sometimes injure self-tissues. Dysfunctional …

HLA-DRB1 and DQB1 alleles in Japanese type 1 autoimmune hepatitis: The predisposing role of the DR4/DR8 heterozygous genotype

S Oka, H Furukawa, M Yasunami, A Kawasaki… - PloS one, 2017 - journals.plos.org
Objective Autoimmune hepatitis (AIH) is a chronic progressive liver disease. AIH is
composed predominantly of type 1 in Japanese populations. The genetic and environmental …

Genetic risk factors for autoimmune hepatitis: implications for phenotypic heterogeneity and biomarkers for drug response

T Higuchi, S Oka, H Furukawa, S Tohma… - Human Genomics, 2021 - Springer
Autoimmune hepatitis (AIH) is a rare chronic progressive liver disease with autoimmune
features. It mainly affects middle-aged women. AIH is occasionally complicated with liver …

HLA-DRB1 alleles of susceptibility and protection in Iranians with autoimmune hepatitis

R Baharlou, A Faghihi-Kashani, F Faraji… - Human Immunology, 2016 - Elsevier
Autoimmune hepatitis (AIH) is an uncommon autoimmune liver disease of unknown etiology.
The aim of this study was to determine the frequency of HLA-DRB1 alleles in Iranian patients …

MHC genes linked to autoimmune disease

P Deitiker, MZ Atassi - Critical Reviews™ in Immunology, 2015 - dl.begellhouse.com
Autoimmune diseases (ADs), or autoinflammatoiy diseases, are growing in complexity as
diagnoses improve and many factors escalate disease risk. Considerable genetic similarity …