Interleukin-1 beta (IL-1β) is induced by inflammatory signals in a broad number of immune
cell types. IL-1β (and IL-18) are the only cytokines which are processed by caspase-1 after …

Inflammation is a crucial function of the innate immune system that protects against
pathogens and initiates specific immunity. Acute inflammation is a rapid and self-limiting …

A causative relationship between chronic inflammation and cancer has been postulated for
many years, and clinical observations and laboratory experiments support the hypothesis …

Abstract Interleukin-1 (IL-1) includes a family of closely related genes; the two major
agonistic proteins, IL-1α and IL-1β, are pleiotropic and affect mainly inflammation, immunity …

Epidemiological and experimental observations support the hypothesis that chronic
inflammation contributes to cancer development and progression; however, the mechanisms …

Interleukin-1 (IL-1) represents a family of two agonistic proteins, IL-1α and IL-1β, that are
pleiotropic and affect hemopoiesis, inflammation, and immunity. In the context of the …

The interleukin‐1 (IL‐1) family consists of two major agonistic proteins, IL‐1α and IL‐1β,
which are pleiotropic and affect mainly inflammation, immunity, and hemopoiesis. The IL‐1 …

The haematogenous phase of cancer metastasis facilitates the transport of metastatic cells
within the blood and incorporates a sequence of interactions between circulating …

The abscopal effect is potentially important for tumor control and is mediated through
cytokines and/or the immune system, mainly cell-mediated immunity. It results from loss of …

In addition to the genomic alterations that occur in malignant cells, the immune system is
increasingly appreciated as a critical axis that regulates the rise of neoplasms and the …